On January 10 th, a book called"Stop issuing performance pay scheme for COVID-19 project"The document was circulated on the Internet and signed by Beijing Kexing Zhongwei Biotechnology Co., Ltd., which mentioned that the company’s COVID-19 vaccine has been completely discontinued and the company has no COVID-19 vaccine products for sale at present.

At noon on January 10th, Jimu journalist called the product consultation hotline of Kexing Holding Biotechnology Co., Ltd., and the staff confirmed it.Kexing’s COVID-19 vaccine has been discontinued. If you still need to inject this product, you should ask the local CDC if it is in stock.

It is worth noting that there are still a variety of vaccines for new strains that can be injected in various parts of China.

Kexing COVID-19 vaccine has been discontinued.

Many companies have "got off the bus" before.

According to Jimu News, on January 10th, a document named "Stop Issuing Performance Pay Scheme for COVID-19 Project" was spread on the Internet. The date of signing the scheme was January 9th, and it was stamped with the official seal of Beijing Kexing Zhongwei Biotechnology Co., Ltd., which mentioned that at this stage, the company has stopped production of COVID-19 vaccine and the company has no sales of COVID-19 vaccine products at present, and the company decided to stop issuing performance pay for COVID-19 project for existing employees from January 2024.

Beijing Kexing Zhongwei Biotechnology Co., Ltd. is a subsidiary of Kexing Holding Biotechnology Co., Ltd. At noon on January 10,The staff of the product consultation hotline of Kexing Holding Biotechnology Co., Ltd. confirmed that at present, the COVID-19 vaccine of Kexing of the company has been discontinued. If the product needs to be injected, it is necessary to ask the local CDC if it is in stock.As for the authenticity of the online transmission of "Stop Sending Performance Pay Scheme for COVID-19 Project", the other party said it was unclear, and she was only responsible for product consultation.

In fact, since 2023, a number of companies that have been developing COVID-19 vaccine have either announced a change of direction or stopped investing, or their financial data reflect the "sequela" of "slow sales" of COVID-19 vaccine.

On July 19th, 2023, COVID-19 Microorganism Tianci Factory, one of the three musketeers of domestic mRNA vaccine, suspended its trial operation because there was no demand for vaccine production in the near future. All this was only two and a half years after it obtained the clinical approval of COVID-19 mRNA vaccine in January 2021. At that time, COVID-19 mRNA vaccine of Microorganism was the second domestic COVID-19 mRNA vaccine that entered the clinical stage.

For COVID-19 vaccine, Clover Bio, a Hong Kong-listed company, can be described as "putting all your eggs in one basket". In June, 2022, Clover Bio announced that it would give priority to the allocation of all resources to COVID-19 vaccine project, suspend the investment in the other three clinical pipelines, and reduce the investment in non-COVID-19 projects and new projects. In December 2022, COVID-19 vaccine SCB-2019(CpG 1018/ aluminum adjuvant), a recombinant protein of clover, was put into emergency use in China, and was officially launched for the first time in February 2023.

However, in the semi-annual report of 2023, Clover Bio said that due to the ever-changing and low overall demand for COVID-19 vaccine from China and countries around the world since 2023, the company predicted that COVID-19 vaccine sales in 2023 would not bring meaningful financial contribution. Its vaccine layout turned to respiratory diseases such as RSV and influenza.

In April 2023, the "low-cost operation notice" of Shangyao Kangxinuo was spread on the Internet. The content of the notice shows that it is decided to suspend the production line from April 4 for a period of 180 days. According to Red Star News at that time, the staff of Kangxinuo patient answering hotline introduced that the COVID-19 (vaccine) production line here was temporarily suspended, and there was no problem here at the headquarters. Now the demand for COVID-19 vaccine is not so great, so the production line of Shanghai Kangxinuo COVID-19 (vaccine) has been temporarily stopped, which will not affect other aspects.

Chang Rongshan: Inactivated vaccine is not recommended at present.

In February 2023, a research paper published by domestic researchers in the latest issue of China CDC Weekly stated that,"Although the protective efficacy of the third dose of Kexing inactivated vaccine can be improved to more than 70% within one month after homologous inoculation, its predictive efficacy will gradually decline to less than 50% after six months."

For COVID-19 infected people whose clinical endpoint is "COVID-19’s symptoms", the research results show that after 28 days and 6 months of intensive immunization, the protective effect of three doses of inactivated Kexing vaccine is only about 30% and 10%. Among them,The predicted protective effect of three doses of Kexing inactivated vaccine on Omicron BA.4/5 is even lower.

According to the interface news, virologist Chang Rongshan reminded that,Inactivated vaccine is not recommended at present.It pointed out that the antigenicity of the current epidemic strains has changed greatly, and the effect of inactivated vaccine will be much worse than that of other technological vaccines."It is best to play mRNA vaccine and recombinant protein vaccine."

According to JingJing. com, Xu Yue, an insider of a company that had previously researched and developed vaccines in COVID-19, said, "The research and development cost is one aspect, but the key is that you have developed it, and the virus has mutated, so the research and development speed can’t keep up at all. Vaccine iteration is too fast, and enterprises really can’t afford it, especially the cost of clinical trials. Before it is commercialized, the vaccine will be outdated first. "

Xu Yue told reporters that unlike the flu virus, which may go round and round, Covid-19 has been upgrading all the way, and the popular virus will not come again, and the old virus will not come. Therefore,Once the new COVID-19 vaccine appears, the old vaccine can be said to be "out of the historical stage".

A number of XBB vaccines were approved for use.

However, people’s willingness to vaccinate has obviously decreased.

According to Jingjing.com, on December 28th, 2023, the National Health and Wellness Commission held a press conference on the prevention and treatment of respiratory diseases in winter. Peng Zhibin, director of the Department of Respiratory Infectious Diseases of the Infectious Diseases Management Office of China CDC, said that recently, the spread of JN.1 (the second-generation sub-branch of BA.2.86 mutant in Omicron, Covid-19) has risen rapidly abroad and has become the main epidemic strain.

"The mutant JN.1 belongs to Omicron. Recently, according to the existing evidence, the World Health Organization believes that JN.1 has strong transmission ability and immune escape ability, but there is no evidence to suggest that its pathogenicity is enhanced. Previous infection and vaccination with XBB (Omicron subtype variant strain) vaccine have a cross-effect of immune protection, and it is predicted that the public health risk brought by it is low. " Peng Zhibin said.

At present, many XBB vaccines have been approved for emergency use in China. In June, 2023, the recombinant trivalent Covid-19 (XBB+BA.5+Delta mutant) trimer protein vaccine (hereinafter referred to as WEEK XBB vaccine) was put into emergency use in a certain range. In December, companies such as Shenzhou Cell, Kangxinuo and Livzon Group also announced that COVID-19 vaccine was included in emergency use.

According to the interface news, a domestic vaccine industry practitioner said,At present, the proportion of people’s willingness to vaccinate COVID-19 vaccine has obviously decreased, and the official has not clarified the requirements for vaccination indicators.All this makes "promoting vaccination in COVID-19" less urgent than before, which reduces the motivation of CDC. He said, "For example, if a company has a product approved, as long as it is developed and produced, the company will definitely want to be recognized in the market, and there is no situation in which the company is not enthusiastic. But in fact, from the step of bidding access, many provinces and cities have no enthusiasm. "

Rong Shan, a virologist, also said that the public is not willing to vaccinate COVID-19 vaccine at present. If COVID-19 vaccine is purchased, but not many people come to vaccinate it, it will easily lead to a backlog. Unlike ordinary commodities, vaccines have strict requirements for transportation and storage, and they will be wasted if they are not used after expiration.

Original title: Kexing COVID-19 vaccine has been discontinued! Many companies have long since "got off the bus", inactivated vaccines have not been recommended, and many XBB vaccines have been approved.

On March 23, 2023, Du Zhaocai attended the annual work conference of key cities of national football development.

According to the website of the State Commission for Discipline Inspection of the Central Commission for Discipline Inspection on April 1, Du Zhaocai, a member of the Party Group and Deputy Director of the State Sports General Administration, is suspected of serious violation of the law and is currently undergoing disciplinary review and supervision investigation by the State Commission for Discipline Inspection. Du Zhaocai is currently the party secretary and vice-chairman of China Football Association, and he is also the highest-ranking official in the anti-corruption storm in football.

Du zhaocai.

Nine people were dismissed, and Du Zhaocai was the highest-ranking official.

According to public information, in the past 141 days, nine related persons of China Football Association have been investigated. As early as November 26, 2022, former China men’s football coach Li Tie was suspected of violating the law; With the final of the FA Cup, the last event of China football in the 2022 season, ending in mid-January 2023, the anti-corruption storm once again set off a climax.

On January 19, 2023, Liu Yi, former secretary general of China Football Association, accepted the supervision and investigation, and Chen Yongliang, executive deputy secretary general of China Football Association and Minister of State Administration, accepted the review and investigation; On February 14th, China Football Association President Chen Xiaoyuan was investigated.

At the "Ministerial Channel" of the National People’s Congress this year, Gao Zhidan, director of the State Sports General Administration, said in response to questions related to the "three big balls" that, realistically speaking, for a long time, the development of the three big balls in China, especially the men’s events, was not satisfactory, the level of men’s football dropped all the way, and there were many chaos in the football industry, which formed a strong contrast with the requirements and expectations of the CPC Central Committee and the people of the whole country.

Gao Zhidan said, we should focus on the outstanding problems in the current "Three Balls" work, such as lack of spirit, lack of righteousness, and weak style of work, and persist in changing our style of work, strengthening our responsibility, and grasping implementation. Resolutely crack down and severely punish corruption and fake gambling in football and other fields, correct the wind and discipline, be strict in discipline, improve the system, strengthen the rules, and comprehensively repair and reconstruct the good ecology of the healthy and sustainable development of the’ three big balls’.

On March 27th, The Politburo Standing Committee (PSC) of the CPC and Li Xi, leader of the Central Inspection Work Leading Group, attended the National Inspection Work Conference and the first round of the 20th Central Inspection Mobilization Deployment Meeting and delivered speeches. Li Xi stressed that to carry out the mobile patrol of the State Sports General Administration, we should focus on fulfilling the party’s leadership functions and responsibilities, implementing the major decision-making arrangements for building a sports power, and thoroughly find out and promote the solution of corruption and deep-seated institutional mechanisms in the sports field, especially in the football field, so as to provide a strong guarantee for building a sports power.

Du zhaocai.

After the two sessions, football anti-corruption refreshed the official level record.

On March 24th, Wang Xiaoping, director of the Commission for Discipline Inspection of China Football Association, and Huang Song, minister of competition department, were suspected of serious violation of discipline and law, and were investigated. On March 29th, Yu Hongchen, former vice chairman of China Football Association, was investigated, and Dong Zheng, former general manager of Super League Company, was investigated. It is worth mentioning that, as the chairman of the current IAAF, Yu Hongchen was a bureau-level cadre, and at that time he was already the first bureau-level cadre to fall in the anti-corruption storm in football. ?

Du Zhaocai, as the deputy director of the General Administration, is a deputy ministerial-level cadre, which has set a new record for football anti-corruption officials. In fact, the anti-corruption storm in football started at the end of 2009, and the highest-level officials such as Xie Yalong and Nan Yong were also limited to the bureau level. This time, the deputy ministerial-level cadres were dismissed, and their ranks were also the highest among the officials who were dismissed in previous football anti-corruption storms.

According to public information, Du Zhaocai, 63, who is currently the deputy director of the State Sports General Administration and the party secretary and vice chairman of the China Football Association, once served as a director of the FIFA Council, chairman of the AFC Referee Committee, executive chairman of the China Organizing Committee of the 2023 AFC Asian Cup and chairman of the East Asian Football Association.

Du Zhaocai’s personal work experience began to intersect with football in 2017-from June 2017, Du Zhaocai was appointed as the assistant director of the State Sports General Administration and the party secretary of the China Football Association by the director of the Tianguan Center; In October 2018, he was promoted to deputy director of the General Administration, responsible for football-related work; In 2019, he served as vice chairman of China Football Association and director of FIFA Council. In April last year, Du Zhaocai was elected as the new president of the East Asian Football Association (from 2022 to 2026). At the beginning of this year, Du Zhaocai failed to run for FIFA director, and he ranked last among the seven candidates.

According to official website, the State Sports General Administration, Du Zhaocai is responsible for football-related work, docking the inter-ministerial joint meeting of FIFA, AFC and the State Council football reform and development, and is responsible for the training and participation of national football teams at all levels, as well as the bidding and preparation of various events held in China, as well as youth football and mass football; Be responsible for the training and competition of track and field, swimming, synchronized swimming, diving and other summer events, and the preparation of various events held in China; And other work assigned by the main responsible comrades. Instruct the Football Association and contact the Football Development Foundation; In charge of track and field center and swimming center, guiding the work of track and field association.

Du zhaocai.

He has repeatedly denounced football corruption in public.

According to the Nanfang Daily, Du Zhaocai has repeatedly denounced football corruption in public-at the National Conference on Competition Discipline and Anti-Doping Work in the Football Industry held in August 2022, Du Zhaocai emphasized that the competition discipline and anti-doping problems, especially the problem of "fake gambling on the black", are the concentrated expression of unhealthy trends in the football industry and a cancer that affects the healthy development of the football industry.

"The vast number of football practitioners should fully understand the special significance of competition discipline and anti-doping work to football work, thoroughly investigate and analyze the problems, take resolute and effective measures to promote competition discipline and anti-doping work, crack down on the rising trend of’ fake gambling on black’ in football field with zero tolerance, create a clean and healthy football style, and promote the healthy development of football in China." Du Zhaocai said.

Just about half a month ago, the Chinese Football Association held a meeting of all cadres. At the meeting, Du Zhaocai said that in the face of the outstanding problems in the current football industry, we must have the courage to face the problems directly.

"Deeply learn from the lessons of a series of recent corruption cases, learn from mistakes, learn from cases, promote reform by cases, find out the reasons, plug loopholes, improve systems and mechanisms, be brave in taking responsibility and fighting, manage and solve ideological problems such as bad tendencies and negative slack in the association, strengthen confidence, make full efforts, change style, break through difficulties, get back on its feet, and strive to open up a new football in China.

According to the official website of the Football Association, on March 23rd, the annual work conference of key cities for national football development was held in the National Football Training Base (Xianghe). Du Zhaocai attended the meeting and delivered a speech.

After Du Zhaocai’s fall, only two vice-chairmen of the Football Association remained in operation.

There are only two vice presidents left in the Football Association to keep running.

According to Beijing Youth Daily, Du Zhaocai’s last public appearance in China Football Association was on the afternoon of March 24th. On the morning of the same day, the news that Huang Song, director of the Competition Department of China Football Association, and Wang Xiaoping, director of the Disciplinary Committee of the Association, were taken away for investigation on suspicion of violating discipline and law was confirmed by official channels.

On the afternoon of the same day, the China Football Association made a briefing on the situation of these two people internally, and at the same time took this opportunity to give a warning education to all middle-level cadres of the Football Association again. The form was the same as that of the anti-corruption warning meeting held after the original China Football Association President Chen Yuyuan, former Secretary-General Liu Yi and Executive Deputy Secretary-General Chen Yongliang were taken away for investigation.

It is worth noting that Du Zhaocai never appeared in the office of the Football Association after attending the anti-corruption warning meeting of the Football Association and speaking at the meeting. This week, Gao Zhidan, director of the General Administration of Sports, and his party went to Liaoning for investigation, and Du Zhaocai was not among them.

After Chen Xiaoyuan and Liu Yi were investigated, the daily work of the Football Association was always presided over by Du Zhaocai. Now, under the investigation of Du Zhaocai, there are only two vice-chairmen in charge of specific business, Gao Hongbo and Sun Wen, secretary of the Discipline Inspection Commission Yan Zhanhe and deputy secretary-general David He, in China Football Association.

Who will be responsible for the daily work next remains to be determined. Therefore, the outside world is also worried that whether the new season Super League can start on April 15th as scheduled will be marked with a big question mark.

How to troubleshoot RAID 5 in the server

　　Due to the continuous progress of technology, different types of servers have different treatment methods after RAID 5 failure.

　　At present, the network topology structure of large-scale application programs generally adopts C/S structure or B/S structure, and at least one server with a large database needs to be placed in the central computer room. Considering the security and reliability of the server, RAID (Redundant Array of Inexpensive Disks) is usually used for redundant backup of the server’s disks. Among them, RAID 5 array level is parity disk array without independent parity disk, which adopts data blocking and independent access technology, can process multiple access requests in parallel on the same disk, and allows any hard disk in the array to fail.

　　In practical application, due to some inevitable objective reasons, some array failures may occur. The most common situation is that the hard disk automatically goes offline, and the online status is displayed as DDD (invalid disk drive), and the hard disk has physical or logical failure. If it is a physical fault, only the hard disk can be replaced; If it is a logical fault, it can be repaired by targeted technology to restore the online state of the hard disk, continue to maintain the striped distribution of the hard disk data in its original array, and continue the consistency of the data storage system.

　　However, the data recovery of some old HP servers (such as HP LH6000) is different from that of new HP servers (such as HP ProLian series servers). Therefore, different servers handle RAID 5 failures differently. I have been in contact with the data failure of RAID 5 array card caused by unexpected power failure of two servers, and solved the problem by adopting different strategies.

Fault repair

　　One is HP LH6000 server, and four 18GB hard disks are made into RAID 5 disk array, and its array card is NetRaid. The other is HP ProLian ML370 server. Four 146GB hard disks are made into RAID 5 disk array, and its array card is Smart Array 642 with Hot Spare hard disk. Both operating systems are Window 2000 and the database is Server 2000.

　　The fault of HP LH6000 is as follows: one hard disk is flashing red light, and the machine is still running normally, but it will not be long before the system can not run normally, and then it is found that the red light of another hard disk is flashing.

The solution is as follows:

　　1. start the server, and press Ctrl+M to enter the NetRaid management program when self-checking to the array. Check the array information and find that the hard disk status is Failed, and use the modified configuration to forcibly set a hard disk to OnLine. Restart the server, the hardware self-check before entering the system is invalid, and the startup fails.

　　2. Start the server, and press Ctrl+M to enter the NetRaid management program when self-checking to the array. Select the disk array, manually Fail the hard disk that was originally hung OnLine, and then manually set another Failed hard disk to OnLine, and restart the server to enter the system.

　　3. After checking that the system and database are running normally, enter the array configuration tool and manually set the Failed hard disk to Rebuild, and then restart the server after 100% reconstruction. All arrays and systems are restored to their original state.

　　Another server running ERP system (HP ProLiant ML370) is configured as a RAID 5-level disk array by four 146GB hot-swappable hard disks through RAID cards (Smart array array cards). One of the hard disks suddenly broke down during operation. Server RAID 5 automatically enables the Hot Spare hard disk to logically replace the damaged hard disk. The data access task of the whole hard disk still runs completely in the original reading and writing process sequence, and the application program and database have no influence.

　　Check the hard disk status through the ACU tool that comes with HP, and find that the hard disk with red light warning is offline. If there are two red lights on Raid 5 in HP ProLiant server, it indicates that the system has crashed and the database cannot be accessed, but the system will not shut down automatically. When the second hard disk is red, the data can’t be recovered by conventional means, so we have to pay a professional third-party data recovery company to recover the data.

　　Therefore, for the old HP LH6000 series servers, the array design is quite different from that of the current HP ProLiant series servers. As far as the operation method is concerned, there are many options for the array operation method of HP LH6000 server, including deleting the array again and rebuilding it after the array fails, and the initialization is also manually selected. However, the initialization of HP ProLiant series server array is automatically performed in the background after the array is configured, so the ProLiant series server cannot reconfigure the array after an array error.

　　The HP LH6000 server will cause the disks in the array to be disconnected for other unexpected reasons, so the maintenance personnel can manually choose Online or Offline, Rebuild, etc. to restore the data. However, the current HP ProLiant series servers will no longer have the phenomenon of disk disconnection in the array like the old servers, so when the hard disk is red, it is basically damaged and needs to be replaced. Of course, you can choose to Rebuild the hot-plug hard disk and see if the hard disk can be used for a while.

Do a good job of technical backup

　　From the above two examples, it can be seen that the troubleshooting of Raid 5 disks of servers of the same brand and different series is different because of their different embedded technologies. But after Rebuild the data, the data was saved, from which the following experiences can be drawn:

　　We believe that any advanced technical means is not foolproof. If you want to ensure data security, you must do a good job of backup, and it is best to do a remote backup of the database once a day. Spare at least one new hard disk. It should be pointed out that the hard disk that joins the array must be greater than or equal to the capacity of the failed hard disk.

　　If conditions permit, the array creation scheme of "RAID 5+ hot spare" is recommended. This way, we have two chances to replace the hard disk before the data is lost. For general applications, only RAID 5 is needed, which can provide data access performance, reliability and maximum disk space at the same time.

　　Administrators must always observe the status of the array, including the yellow warning light of the disk array and the drive status in the management software. Trouble shooting in time. No matter what level of array, data backup should be done before troubleshooting.

　　Throughout modern history, smallpox has held the top spot in killing human beings.

　　Smallpox is also the first infectious disease eliminated by human beings.

　　When future generations are exploring what killed smallpox, the trekking about how human beings overcome diseases step by step has merged into the long river of human medical history.

　　It is necessary for us to wade into this river at any time, go back to the way we came and find hope for the future.

　　The pockmarked emperor and the milkmaid

　　It is mentioned in Huangdi Neijing that "poison" should be used to treat diseases, and the so-called "fight poison with poison". Traditional Chinese medicine began to use this method to deal with smallpox, which existed during the Tang and Song Dynasties. Doctors take out the serous fluid from the abscess of smallpox patients and implant it into the body of healthy people for prevention and treatment, which is called human pox vaccination.

　　During the Wanli and Apocalypse years of Ming Dynasty, various books about human pox appeared. By the Qing dynasty, the method of preventing smallpox by human pox vaccination was widely promoted. Kangxi, the "pockmarked-faced emperor" who had suffered from smallpox, set up a pox clinic under the Tai Hospital and recruited famous doctors. Also in Beijing, a special "acne check chapter Beijing" is set up to take charge of the Eight Banners’ acne prevention. He specially sent people to welcome Ayla Zhang, a well-known folk vaccinia doctor, into the palace to vaccinate the royal family and banners.

　　Jared diamond, an evolutionary biologist and anthropologist, once revealed how the human body can defeat the virus: in the process of resisting a certain pathogen that infects the human body, the human body will gradually form specific antibodies, which makes it unlikely to be infected by the same pathogen again after recovery.

　　In the thousands of years of confrontation between human beings and smallpox, the latter has occupied an absolute advantage for a long time, and "pockmarked face" is so common that people without pockmarked face become special.

　　The 18th century was the age when smallpox ravaged Europe, and the British doctor edward Cenna (1749-1829) devoted himself to studying the solution. He noticed that almost all the female milkmaids had no "pockmarked faces". The beautiful milkmaid aroused Qinna’s curiosity, and he found one thing in common with them — — Cowpox of a milkmaid.

　　Vaccinia is a virus that can be co-infected by humans and animals, but it does no serious harm to cattle and people. There is a saying in the English countryside that "as long as you have suffered from vaccinia, you will not get smallpox".

　　Since 1788, Qinna began to carry out experiments on animals, using vaccinia of dairy women instead of smallpox patients to fight smallpox. For 8 years in a row, the experiment pointed to the same result, and vaccinia can effectively prevent smallpox.

　　On May 14th, 1796, Qinna conducted the first human experiment. He took the serous fluid Sarah Nelmes, a milkmaid, and inoculated it on the arm of phipps, an 8-year-old boy. Two months later, he inoculated phipps with real smallpox slurry. As a result, the boy was not infected with smallpox, and the previous vaccination seemed to have made him immune.

　　In the following two years, Qinna conducted the same human experiment many times, and the results were the same: all children who had had vaccinia were immune to smallpox virus. In 1798, Chennault announced that smallpox could be prevented by vaccination.

　　Vaccinium vaccination spread rapidly around the world. In 1977, Ethiopia recorded the last case of smallpox in human history. On October 26, 1979, WHO officially publicized that smallpox was eradicated all over the world.

　　This is the first time in human history to win the battle against infectious diseases.

　　Fatal bacteria and life-saving bacteria

　　Although the practical application of vaccinia technology is very successful, scientists are not satisfied. People need to explain theoretically why vaccinia can fight smallpox.

　　In the 1950s, chemist Louis Pasteur confirmed the relationship between diseases and germs, and found that specific microbial pathogens could cause specific diseases. Moreover, he found that the long-term growth toxicity of bacteria on artificial culture medium would be weakened, but the immunogenicity still existed.

　　According to this theory, in 1881, Pasteur artificially attenuated Bacillus anthracis with strong immunogenicity and inoculated it into sheep, which finally proved that sheep inoculated with Bacillus anthracis vaccine would not get the disease again.

　　Rabies virus can not be isolated and cultured like bacteria, but Pasteur confirmed that the pathogenic microorganism causing rabies exists in the spinal cord or brain tissue of sick animals. Therefore, he chose rabbit brain for subculture to obtain attenuated strains, and then successfully made live vaccines.

　　With the development of microbiology and immunology, vaccine is really defined as active immunity preparation for preventing infectious diseases, which is made of pathogenic microorganisms (such as bacteria, rickettsia, viruses, etc.) and their metabolites by artificial attenuation, inactivation or genetic engineering.

　　Based on this method, more vaccines can appear. Attenuated live vaccine made by heating inactivation of Vibrio cholerae; After 13 years and 213 generations of continuous culture on the culture medium, attenuated BCG was obtained.

　　With the development of the discipline, some traditional classical vaccine varieties have been further transformed into new vaccines, and some vaccines that cannot be developed with classical technology have found ways to solve the problem.

　　In 1972, recombinant genetic engineering contributed a lot of technical support and gave birth to recombinant gene vaccine. By using DNA recombinant biotechnology, natural or synthetic genetic material which can induce immune response in protein of pathogen shell can be directionally inserted into bacteria, yeast or mammalian cells, and the vaccine can be made after expression and purification. Nowadays, BCG, recombination vaccines, SARS vaccine, HIV vaccine and highly pathogenic avian influenza vaccine are being studied.

　　Conjugate vaccine appeared in 1980s. Scientists linked sugar molecules with protein (toxoid of Clostridium tetanus or diphtheria) by chemical methods, and developed a conjugate vaccine. Vaccines against pneumonia and meningitis are made in this way.

　　Looking at the present, the vaccine that has attracted much attention is none other than nucleic acid vaccine. Nucleic acid vaccine, also known as gene vaccine or DNA vaccine, transports DNA vaccine to human cells through some carrier (such as nanoparticles), which will guide the cells to produce immune active components, and then the cells will "spit out" these active components to stimulate the human body to obtain corresponding immunity, but it will not cause disease.

　　Nucleic acid vaccine can even transfect food cells, such as inserting hepatitis B virus nucleic acid vaccine into the genome of tomato cells, and inoculating the vaccine when eating tomatoes.

　　Scientific and technological progress brings infinite possibilities, and the new exploration of vaccination methods is also the tireless pursuit of scientists. In addition to traditional injection methods, oral administration, skin patch, nasal spray and improved fruit are all targets.

　　A never-ending struggle

　　With the development of immunology research, people have more and more expectations for vaccines, hoping that they will not only "prevent diseases". Researchers are already in action, trying to achieve the effect of treating diseases or preventing diseases from worsening by inducing specific immune responses. Such vaccine products are therapeutic vaccines.

　　There are many therapeutic vaccines that have been studied all over the world: tumor vaccines used for tumor treatment use tumor antigens for active immunization to stimulate the body’s active specific immune response to tumors to prevent the growth, spread and metastasis of tumors; Vaccines used for the treatment of cardiovascular diseases aim at intervening the immune process to prevent the occurrence and development of atherosclerosis (AS). A Swiss biotechnology company said that CYT006-AngQb, a vaccine used to treat hypertension, has a good clinical development prospect … …

　　On the other hand, when human beings are struggling to move forward, the "perpetrators" of infectious diseases are not willing to be silent. Since 1970s, more than 40 infectious diseases have been discovered in the world, such as HIV virus, avian influenza virus, SARS virus, mad cow disease prion, monkeypox virus, Lyme virus, Ebola virus, Legionella, Vibrio cholerae O139 and so on. People’s common influenza viruses are constantly innovating. For example, after the "Spanish flu" caused by H1N1 virus, the "Asian flu" and the "Hong Kong flu" were staged by H3N2 subtype virus. Or a lower-grade flu, it is staged almost every few years in Europe, America and Asia. There are also new viruses that have never met each other, eyeing and hiding in the dark.

　　"The only competitor competing with humans for the dominance of the earth is the virus." The words of lederberg, the winner of the Nobel Prize in Physiology or Medicine in 1958, sounded like an alarm bell. In the past two hundred years, the confrontation between human beings and germs was the fiercest. For the first time, we turned the tables, stood in a pre-emptive position, and seized the throat of the biggest killer of human beings. Compared with the end of the 19th century, the average life expectancy of human beings has been extended for several decades.

　　We have opened the "box" of vaccines. Overcoming the challenge of disease again and again makes us believe that disease creates problems and also provides understanding.

　　Huaxi Dushi Bao-cover journalist Li Yuanli

　　[References]

　　1. zhangfang, from human pox to cowpox [J], Science World, 06, 2018;

　　2. [America] jared diamond, Guns, Germs and Steel, Shanghai Translation Publishing House;

　　3. Huang Jiandong, the milestone of human conquest of smallpox — — Jenner’s Invention of Vaccinium Inoculation [J], Invention and Innovation, 2003, (9): 42-43;

　　4, Liu Xueli, China’s ancient immune thought and human pox vaccination [J], Medicine and Philosophy, 1993 (11);

　　5. Kou Yi, Brief Introduction of Three Vaccine Revolutions [J], Chinese Journal of Medical History;

　　6. Plotkin, Vaccine Science (5th Edition) (Fine), People’s Health Publishing House, 2011;

　　7. Xie Zhongping and Li Qihan, Fighting Infectious Diseases: Application and Development of Vaccines, 2007.

　　CCTV News:The National Health and Wellness Commission held a press conference on December 2 to introduce the prevention and treatment of respiratory diseases in winter and answer media questions.

Xinhua News Agency: Vaccine has played a key role in the prevention and control of influenza. At present, influenza has entered the high season. Is it too late to vaccinate now?

Wang Dayan, Director of National Influenza Center, Institute of Virology, China CDC:Among the prevalent respiratory diseases, influenza, COVID-19 and pneumococcal infection all have corresponding types of vaccines. The influenza vaccine has been used in the world and China for decades. Scientific research and vaccination practice have fully proved that the influenza vaccine is safe, effective and a mature vaccine. Influenza vaccination can effectively reduce infection, even if it is infected, it can also reduce the incidence, and even if it is infected, it can also reduce the severity of the disease.

At present, it is the high season of influenza, and it is still effective to vaccinate people who have not been vaccinated with influenza before. It is recommended that you vaccinate with influenza as soon as possible. Here, I especially point out that people over 6 months can be vaccinated with influenza, especially for high-risk people such as children, the elderly and patients with chronic diseases. After being infected with influenza, the risk of severe illness is higher. Vaccination with influenza can effectively reduce the risk of developing into severe illness and death. I hope everyone will actively vaccinate.

Practice at home and abroad has proved that the use of vaccine is one of the most economical and effective preventive measures, and the vaccine is safe. As long as it is vaccinated in professional institutions as required, it can have good results, especially for the elderly and children, and should actively vaccinate against influenza to ensure the normal pace of life and study.

Actress Aya Sugimoto was recently invited to shoot a group of public service advertisements for PETA, an animal protection association. On the 17th, she took a formal photo shoot in a studio in Tokyo.

　　Although she was used to nudity in filming, Aya Sugimoto felt a different sense of tension that day. Only one piece with the words "Fur? It’s better to be naked. "The advertisement board covers her chest. She said," So far, I feel naked is the feeling of wearing another suit, but this time I have a different sense of tension. I seem to have taken off all my clothes. " Having said that, the actress, who is famous for her sexy and erotic lines, still showed a provocative and dangerous expression when facing the camera. "I stopped wearing fur two years ago, hoping I could face the eyes of those dead animals." It seems that Erotic Queen still has a positive attitude and decisive action in environmental protection. I believe this is also the place that PETA invited her to appear in this group of advertisements.

Bulletin of the Seventh National Population Census in Yueyang [1] (No.1)

-population situation of the whole city

Yueyang statistics bureau

Yueyang No.7 Ci National Population Census Leading Team Office

June 21, 2021

According to the Statistics Law of the People’s Republic of China, the Regulations on National Census and the decision of the State Council, China conducted the seventh national census at 0: 00 on November 1, 2020 [2]. Under the strong leadership of the municipal party committee and the municipal government, with the support and cooperation of all census objects, and through the hard work of census institutions at all levels and the vast number of census staff, the census site registration and the summary of census main data were successfully completed. The main data of the city are now published as follows:

I. Permanent population

The resident population of the city [3] is 5,051,922, which is 424,162, a decrease of 7.75% compared with 5,476,084 in the sixth national census in 2010.

Second, other people’s families

There are 1,693,071 family households and 57,633 collective households in the city, with a family population of 4,666,924 and a collective population of 384,998. The average population of each household is 2.76, which is 0.61 less than the sixth national census in 2010.

Note and release:

[1] The data in this bulletin are preliminary summary data.

[2] The objects of census registration refer to natural persons who are in People’s Republic of China (PRC) and China citizens who are outside People’s Republic of China (PRC) but have not settled, excluding overseas personnel who stay in People’s Republic of China (PRC) for a short time.

[3] The permanent population includes people who live in the streets of this township and whose household registration is in the streets of this township or whose household registration is to be determined; People who live in the township streets and leave the township streets where their registered permanent residence is located for more than half a year; People with registered permanent residence in the streets of this township who have been out for less than half a year or have worked and studied abroad.

[4] A household refers to a household composed of people who are mainly family members and live together.

Bulletin of the Seventh National Population Census in Yueyang [1] (No.2)

-Population situation in counties and urban areas

Yueyang statistics bureau

Yueyang No.7 Ci National Population Census Leading Team Office

June 21, 2021

According to the results of the seventh national census, the permanent population of 9 counties and cities in Yueyang City at 0: 00 on November 1, 2020 is now announced as follows:

Among the 9 counties and cities, there are 6 counties and cities with a population of 500,000 to 1 million, namely Yueyanglou District, Pingjiang County, Miluo City, Xiangyin County, Yueyang County and Huarong County; There are two counties and cities between 200,000 and 500,000 people, namely Linxiang City and Junshan District; There is one in the counties and cities with less than 200,000 people, which is Yunxi District. Among them, the top three counties and cities have a total of 2563759 people, accounting for 50.75% of the city’s permanent population. The population of urban area [3] is 1335692, accounting for 26.44%.

Table 2-1 Resident Population in Counties and Urban Areas [4]

                                                                                                                                                                     Unit: person,%

Notes:

[1] The data in this bulletin are preliminary summary data.

[2] refers to the proportion of the permanent population of counties and urban areas in the city’s permanent population.

[3] Urban areas refer to Yueyang Tower District, Yunxi District and Junshan District.

[4] Some data are not equal to the total of sub-items due to rounding.

Bulletin of the Seventh National Population Census in Yueyang [1] (No.3)

-Gender composition of the population

Yueyang statistics bureau

Yueyang No.7 Ci National Population Census Leading Team Office

June 21, 2021

According to the results of the seventh national census, the gender composition of permanent residents in 9 counties and cities of Yueyang City at 0: 00 on November 1, 2020 is now announced as follows:

First, the gender composition of the city’s population

Among the permanent residents in the city, the male population is 2586621, accounting for 51.20%; The female population is 2465301, accounting for 48.80%. The sex ratio of the total population (100 females, the ratio of males to females) is 104.92, which is 2.27 lower than the sixth national census in 2010.

Second, the gender composition of the population in counties and cities

Among the nine counties and cities, Yueyanglou District with the lowest sex ratio is 101.32, and Yunxi District with the highest sex ratio is 110.70.

Table 3-1 Gender Composition of Population in Counties and Cities

                                                                                                                                                                                   Unit:%

Notes:

[1] The data in this bulletin are preliminary summary data.

Bulletin of the Seventh National Population Census in Yueyang [1] (No.4)

-age composition of the population

Yueyang statistics bureau

Yueyang No.7 Ci National Population Census Leading Team Office

June 21, 2021

According to the results of the seventh national census, the age composition of permanent residents in 9 counties and cities of Yueyang City at 0: 00 on November 1, 2020 is now announced as follows:

First, the age composition of the city’s population

Among the permanent residents in the city, the population aged 0-14 is 932382, accounting for 18.46%; The population aged 15-59 is 3,095,500, accounting for 61.27%; The population aged 60 and above is 1024040, accounting for 20.27%; The population aged 65 and above is 757,815, accounting for 15.00%. Compared with the sixth national census in 2010, the proportion of population aged 0-14 increased by 2.44 percentage points, the proportion of population aged 15-59 decreased by 8.83 percentage points, the proportion of population aged 60 and over increased by 6.39 percentage points, and the proportion of population aged 65 and over increased by 5.88 percentage points.

Table 4-1 Age Composition of Population in the City

                                                                                                                                                              Unit: person,%

Second, the age composition of the population in counties and cities

In terms of counties and cities, there is one population aged 15-59 who accounts for more than 65%, four between 60% and 65%, and four between 55% and 60%.

Table 4-2 Population Age Composition of Counties and Urban Areas [2]

                                                                                                                                                                           Unit:%

fill
Interpretation:

[1]
The data in this bulletin are preliminary summary data.

[2]
Due to rounding, some data are not equal to the total of sub-items.

Bulletin of the Seventh National Population Census in Yueyang [1] (No.5)

-Education of the population

Yueyang statistics bureau

Yueyang No.7 Ci National Population Census Leading Team Office

June 21, 2021

According to the results of the seventh national census, the basic situation of education of permanent residents in 9 counties and cities of Yueyang City at 0: 00 on November 1, 2020 is now announced as follows:

I. Population with education level

Among the permanent residents in the city, 489,592 people have a college education. The population with high school (including technical secondary school) education is 1295391; The population with junior high school education is 1684658; The population with primary school education is 1,134,573 (the above-mentioned people with various education levels include graduates, dropouts and students in various schools). Compared with the sixth national census in 2010, the number of people with university education per 100,000 people increased from 6,852 to 9,691; The number of people with high school education has increased from 22,977 to 25,642; The number of people with junior high school education dropped from 38,325 to 33,347; The number of people with primary school education dropped from 23,343 to 22,458.

Table 5-1 Number of people with various education levels per 100,000 population in counties and urban areas

                                                                                                                                                              Unit: person/100,000 people

Second, the average length of education [2]

Compared with the sixth national census in 2010, among the permanent residents in the city, the average years of education of the population aged 15 and above increased from 9.58 to 10.06. Among the 9 counties and cities, 3 have an average education period of more than 10 years, and 6 have a period of 9 to 10 years.

Table 5-2 Average years of education of population aged 15 and above in counties and urban areas

                                                                                                                                                                     Unit: year

Iii. illiterate population

Among the permanent residents in the city, the illiterate population (illiterate people aged 15 and above) is 64,181. Compared with the sixth national census in 2010, the illiterate population has decreased by 32,414, and the illiteracy rate [3] has dropped from 1.76% to 1.27%, a decrease of 0.49 percentage points.

Notes:

[1] The data in this bulletin are preliminary summary data.

[2] The average length of education is calculated by converting various education levels into the average number of years of education. The specific conversion criteria are: primary school =6 years, junior high school =9 years, high school =12 years, and junior college and above =16 years.

[3] The illiteracy rate refers to the proportion of illiterate people aged 15 and above in the permanent population.

The latest news of the situation in Russia and Ukraine has attracted the attention of all parties.

On February 12, the Global Times quoted the US Wall Street Journal as reporting on February 11 that the General Intelligence Department of the Ukrainian Ministry of National Defense said on the same day that the Russian army was using the "Star Chain" system developed by SpaceX on a large scale at the front line. In response, SpaceX CEO Musk responded urgently, "Some false news said that SpaceX is selling’ Star Chain’ terminals to Russia. This is absolutely wrong. "

On February 12th, local time, the Kremlin responded that elon musk’s "Star Link" satellite Internet system was neither certified for use in Russia nor officially supplied to Russia, so it could not be used.

At present, Musk’s "Star Chain" business is welcoming a big outbreak. According to a source quoted by Bloomberg, it is estimated that SpaceX’s sales in 2024 will increase to about 15 billion US dollars, in which the sales of "Star Chain" business will exceed the launch business, and the number of users of satellite Internet service will exceed 40 million by 2025. SpaceX’s annual income can reach 30 billion US dollars, and the "Star Chain" project will become the most profitable business.

Musk responded urgently.

On February 12, the Global Times quoted the American Wall Street Journal as reporting on February 11 that the General Intelligence Bureau of the Ukrainian Ministry of National Defense said on the same day that the Russian army was using the "Star Chain" system developed by SpaceX on a large scale near the front line of the Russian-Ukrainian conflict, which might weaken a major battlefield advantage of the Ukrainian army.

According to the report, by using the "star chain" system, Ukrainian frontline troops can communicate safely with Internet applications, so that they can keep in touch without relying on mobile phones or radio signals that are more easily monitored by Russian troops.

Andrei Yusov, spokesman for the General Intelligence Department of Ukraine’s Ministry of National Defense, said that Russian troops are "systematically" using "Star Chain" terminals, which are used by Russian 83rd Air Assault Brigade and other troops, which are fighting near the towns of Cris Chivka and Andrevka in Donetsk region of eastern Ukraine.

The statement did not mention how the Russian army obtained these terminals, for example, whether they were purchased from abroad or seized from the Ukrainian army.

This is the first time Ukraine has issued an official statement on Russia’s alleged use of the Star Chain.

Later on December 11, local time, SpaceX CEO Musk responded urgently.

Musk responded that "some false news said that SpaceX is selling’ Star Chain’ terminals to Russia. This is absolutely wrong. "

Musk wrote on the social platform X: "As far as we know, no’ Star Chain’ terminal is directly or indirectly sold to Russia."

On February 12th, local time, the Kremlin also responded that elon musk’s "Star Link" satellite Internet system was neither certified for use in Russia nor officially supplied to Russia, so it could not be used.

Kremlin spokesman dmitry Peskov said in an interview: "This is not our certified system; Therefore, it cannot be officially supplied here, nor is it officially supplied. Therefore, it cannot be officially used in any way. "

Frequently involved in the Russian-Ukrainian conflict

The Global Times quoted The Wall Street Journal as saying that SpaceX had issued a statement on social platform X on February 8, local time, saying that the "Star Chain" satellite service could not be used in Russia, but did not explain whether this service could be used on the Russian-controlled side of the Russian-Ukrainian front line.

A SpaceX spokesperson did not respond to a request for comment on the 11th.

The report pointed out that although the "Star Chain" terminal could not be purchased in Russia, Ukrainian media reported that the Russian army had purchased the equipment in a third country and brought it to the front. In addition, the Russian army may have seized the "star chain" terminal from the Ukrainian army, so that it can access the "star chain" network. Although SpaceX has the ability to track the "Star Chain" users in a specific geographical location, it may be difficult for the company to determine whether the users are Russian or Ukrainian, especially in front-line areas.

The Wall Street Journal said that since Musk decided to provide "Star Chain" service for Ukraine after the outbreak of the Russian-Ukrainian conflict, the use of the "Star Chain" system has always been a politically charged issue.

According to the report, the "Star Chain" system is considered to be crucial to the actions of the Ukrainian army, so that when SpaceX said that it could no longer provide access funds for Uzbekistan in 2023, the US Department of Defense and other Ukrainian supporters were forced to agree to pay the fees to maintain the operation of the service.

In September 2023, Musk said that in the early days of the conflict, he rejected Ukraine’s request to start the "Star Chain" service near Sevastopol, Crimea, in order to avoid SpaceX’s direct involvement in Uzbekistan’s plan to attack Russian ships.

Gwen Shotwell, president of SpaceX, said at a meeting earlier that SpaceX had taken measures to restrict the use of the "Star Chain" system in Ukrainian military operations. She said at the time that the company did not intend to make the "star chain" a weapon.

"Star Chain" Outbreak

SpaceX is a space exploration technology company owned by Musk. Its main business includes orbital rocket launch, manned space flight and satellite Internet service. The satellite Internet service is the star chain service, which aims to provide high-speed Internet connection for users around the world through satellite network.

According to Bloomberg, which previously quoted people familiar with the matter, SpaceX’s revenue from rocket launch and starlink business in 2023 is estimated to be about 9 billion US dollars, and its sales are expected to increase to about 15 billion US dollars in 2024.

According to the report, it is estimated that the sales of "Star Chain" business will exceed the launch business in 2024, which will account for most of SpaceX’s total revenue. By 2025, the number of users of satellite Internet services will exceed 40 million, and SpaceX’s annual revenue will reach 30 billion US dollars. The "Star Chain" project will become the most profitable "Golden Bull" business.

Musk has been trying to use the "Star Chain" business unit as an important source of income to fund SpaceX’s capital-intensive projects.

It is reported that "Star Chain" is a low-orbit Internet constellation plan proposed by SpaceX in 2014, with the goal of building a space-based communication system with global coverage, large capacity and low delay, and providing high-speed Internet services on a global scale.

Statistics show that by the end of 2023, "Star Chain" has been applied in 65 countries, serving over 2.3 million users, an increase of over 1.3 million.

According to the latest report of Cloudflare, a network infrastructure company, compared with 2022, American traffic from "Star Chain" increased by more than 150% in 2023.

From a global perspective, according to the statistics of Cloudflare, the internet traffic in the world increased by 25% in 2023, while the traffic of "Star Chain" was twice as much as this data.

It is worth mentioning that in the past year, Musk has strengthened in-depth cooperation with the US military. The most striking thing is that SpaceX has specially created a service product called "Star Shield" for the US military, and in view of the good performance of "Star Chain" on the battlefield in Ukraine, the US Department of Defense also awarded SpaceX a contract worth 70 million US dollars in September 2023.

According to the contract, the Star Shield network will provide end-to-end services for the military through the Star Chain constellation, user terminals, auxiliary equipment, network management and other related services, and on the basis of the Star Chain data encryption service, the Star Shield has been added with additional encryption technology to ensure the security of data processing of the hosted payload, and SpaceX has become the first provider to provide low-earth orbit satellite services for the US military.

Original title: "Sudden! Musk, respond urgently! 》

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　　Song Joong Ki meets fans. On May 14th, the "2016 Song Joong Ki Asia Tour Fans Meeting" was held at the National Olympic Center Gymnasium. Korean artist Song Joong Ki interacted with fans at the meeting, causing fans to scream. Song Joong Ki will also go to Wuhan, Guangzhou, Shenzhen, Shanghai, Hong Kong, Chengdu and Taipei to complete the fan meeting in eight cities in Greater China.

　　I finally waited for you, but I didn’t give up. On May 14th, Song Joong Ki held the first meeting of fans on the Asian Tour in Beijing. Nearly one gymnasium with a capacity of 10,000 people was packed. Song Joong Ki, the "national husband", appeared in the screams of fans with a white shirt and black trousers, and appeared on the lifting platform, just like the prince in every girl’s heart.

On November 15th, at the 22nd Guangzhou International Automobile Exhibition, SAIC unveiled dozens of new energy vehicles with eleven brands including Zhiji, Roewe, Feifan, MG, Datong, Audi, Volkswagen, Cadillac, Buick, Wuling and Baojun.

The models unveiled this time include: Super City Smart SUV brand-new Zhiji LS6, the world’s longest battery life and lowest fuel consumption MPV Roewe iMAX8 DMH Xinluzun, Feifan brand-new R7, global high-standard pure electric rear-drive SUV MGES5, smart and efficient pure electric bus SAIC Datong Dana M1, SAIC AUDI Audi brand "Class B pure electric Sportback" Audi E concept car, Joint venture pure electric head brand SAIC Volkswagen ID. Pure electric family, new American pure electric option Cadillac IQ proud song, the strongest luxury plug-in MPV”GL8 LU Zun PHEV, household large space SUV Wuling Xingguang S, 100,000-class only high-level intelligent driver box Bao Junyue Plus, etc.

It is reported that SAIC has invested nearly 150 billion yuan in research and development in the core technology field of smart electricity, and has obtained more than 26,000 effective patents, successfully launching the "seven technical bases" with international leading technology level, including three complete vehicle platforms of pure electric, hybrid and hydrogen energy, as well as full-stack solutions for batteries, electric drives, super-hybrid systems and smart cars. This year, SAIC officially released the "Seven Technical Bases" 2.0, accelerating the reconstruction of the longboard functional experience of SAIC electric smart cars such as high-level intelligent driving, integrated cockpit, digital chassis and high-efficiency driving, and fully empowering independent joint venture brands to continue to make breakthroughs.

Zhiji Automobile ushered in "Intelligent Great Evolution"

At the Guangzhou Auto Show, Zhiji Auto officially announced that intelligent core technologies such as Linglizard digital chassis, iAd high-order intelligent driving and stunning intelligent cabin ushered in a full-dimensional rejuvenation. For the first time in the industry, Zhiji Automobile realized the deep integration of the intelligent driving domain and the intelligent chassis domain, and the new LS6 and L6 innovatively realized the functions of "lizard turning around" and "pan-tilt body". "Linglizards turn around" makes the map-free NOA realize "two-way, two-lane, automatic U-turn, one pass" for the first time, and at the same time makes medium and large SUVs have the same flexibility as Mini cars; The "pan-tilt body" significantly enhances the stability, safety and comfort of vehicles when they make big bends and sharp bends during high-speed elevated NOA driving.

On the basis of successfully opening only four "national-no map -NOA" in the industry, IM AD 3.0 is upgraded by relying on the "one-stage end-to-end intuitive intelligent driving model". In NOA driving without a map on the central road in the city, you can make the blind area cross the situation and easily bypass obstacles such as puddles. In the face of the unprotected left-turn scene where people and vehicles are mixed, they can play games as sophisticated as old drivers. At complicated intersections, even in the face of unclear road conditions such as no central line and super-wide cars, you can calmly cope and pass smoothly.

The "super smart cabin" also ushered in a major upgrade of software and hardware. The most popular "rainy night mode" adds the function of automatic recognition of pit avoidance; "ISC Intelligent Lamp Language System" can customize the lamp language and convey happiness to others in the most playful way. "Adventure Road Book" deeply combines Tik Tok’s rich video content, enjoying the immersive audio-visual experience in the process of exploration, and adding inspiration for travel. In addition, the trendy technology item "IM MAX Back Smart Screen" cooperates with the unique "three-lying mode" of the new LS6 to realize the freedom of first-class viewing.

DMH Super Hybrid "has the strongest battery life and the best fuel consumption"

Self-owned brand "national team" SAIC Roewe will display Roewe iMAX8 DMH New Land Zun and Roewe D7 DMH World Champion Edition, which have created many world records in the field of blending. Under the full notarization of a third-party authority, Roewe iMAX8 DMH Xinluzun became the "MPV with the longest battery life and the lowest fuel consumption in the world" with the measured battery life of 1536km and CLTC power loss and fuel consumption of 4.71L/100km. At the same time, Roewe D7 DMH World Champion Edition also broke the ceiling of the industry with the achievement of "creating the Guinness World Record for the longest cruising range", and boarded the throne of "Hybrid B-Class Vehicle with the lowest fuel consumption in the world" with the cruising range of over 2208km and the average fuel consumption data as low as 2.49L/100km.

Roewe iMAX8 DMH Xinluzun and Roewe D7 DMH World Champion Edition can achieve far-ahead endurance performance, thanks to the powerful empowerment of SAIC DMH super hybrid system. The system has the industry’s first five-in-one powertrain brain PICU, P1+P3 dual-motor hybrid special gearbox and other hybrid special hardware and software to achieve the strongest endurance and the best fuel consumption index of hybrid power.

Global High-standard "Quality Trams"

As the "export champion of single automobile brand in China", MG brand has brought the newly released "global high-standard pure electric rear-drive SUV" MGES5, which will be listed in the global market gradually in the first quarter of next year. MG ES5, which originated from the exclusive serialization platform of pure electricity of SAIC Nebula, was developed in accordance with the strict European five-star standards, and collected the high standards of Chinese and foreign laws and regulations in terms of interior materials, air quality control and anti-corrosion treatment to provide users around the world with a higher quality driving experience. It integrates eight functions, such as intelligent cruise assistance and lane keeping assistance, covering a variety of complex driving scenarios and providing a convenient and safe driving experience; Applying the "motion sickness relieving system" pioneered by SAIC, it can effectively reduce the motion sickness by 30% and become the leading "tram that never gets motion sickness" at the same level. In addition, the Rubik’s Cube battery of SAIC Zero Combustion Technology equipped with MG ES5 has multiple protections, such as 7×24-hour remote monitoring, early heat dissipation system, automatic pressure relief and explosion-proof valve, with a maximum life of 1 million kilometers, and has maintained a record of "zero spontaneous combustion" so far.

The brand-new R7 of Feifan, which debuted, inherits the core advantages of family products, including a brand-new cockpit that is intelligent and comfortable, the industry’s first 3+1 super-visual intelligent interaction, and a motion sickness relieving system that can effectively solve users’ pain points, refreshing the "intelligent and comfortable" quality experience, injecting new vitality into the medium and large pure electric SUV market, and will be listed in the first quarter of 2025.

"China light passenger is the first choice for developed countries in the world", SAIC Chase will present the "smart and efficient pure electric bus" with M1, which not only has 9 leapfrog spaces, the lowest power consumption of the same class of 17.5kWh and a long CLTC battery life of 405km, but also won the highest safety rating of Euro NCAP platinum in Europe.

Advanced intelligent driving "100,000-level era"

The Baojunyue Plus 2025, which was officially listed at the Guangzhou Auto Show, has mass-produced the end-to-end model to 100,000-class models, bringing users the "100,000-class only high-level intelligent driving box".

The new car is equipped with Lingmiao Intelligent Driving 2.0Max, which is the first model of 100,000-level end-to-end model mass production in the industry. Full-speed intelligent driving assistance, the only urban memory navigation function at the same level, high-speed navigation assistance that can be used and used all over the country, and the strongest active safety capability within 200,000 class make daily travel more efficient, comfortable and safe. At the same time, the industry’s first intelligent parking covers more than 3,000 scenes, the only memory parking at the same level, the only self-selected parking space at the same level and other functions, which deeply solve the parking difficulties of users, and Lingmu Intelligent Driving 2.0 Max truly becomes the most intelligent driving system for users.

New energy vehicles "joint venture top flow"

As the "top joint venture" of new energy in China’s automobile industry, SAIC Volkswagen, SAIC Audi and SAIC-GM will respectively display the "joint venture pure electric sales crown" SAIC Volkswagen ID. Family, "Class B pure electric Sportback" Audi E concept car and "the strongest luxury plug-in MPV" Buick GL8 Luzun PHEV.

At present, the ID family of SAIC Volkswagen has officially entered the period of intelligent rapid penetration, bringing better and smarter quality pure electricity to new energy consumers. The car APP "Intelligent Voice GPT" based on the big language model, the newly blessed Iflytek voice interactive system, the V Mate intelligent assistant supporting voice cloning, the high-order full-journey intelligent driving assistance system with automatic lane change, and the high-class parking housekeeper who realizes remote parking and parking of mobile phones, etc., are full of technology and hard work, which makes users more aware of the "cleverness" of the ID family.

At SAIC Audi booth, the "Class B pure electric Sportback" Audi E concept car is a well-deserved protagonist. It is the young and enterprising embodiment of Audi and can be called a "luxury new species" that subverts the automobile industry. Inherited from Audi’s pure genes, the Audi E concept car perfectly interprets Audi’s unique excellent driving experience. The total output power of its front and rear axle dual motors is as high as 570 kW. With the blessing of quattro four-wheel drive system, the acceleration of zero hundred is only 3.6 seconds. At the same time, under Audi’s scene definition and human-computer interaction design, and integrating SAIC’s "Yinhe" full stack 3.0 electronic and electrical architecture, Audi E concept car has realized the integration of "cabin, driving, calculation and connection", and built a full-scene digital intelligent companion cockpit for drivers and passengers.

As a luxury gold standard hybrid MPV tailored for China market, Buick GL8 Luzun PHEV inherits Buick MPV’s leading product strength and deep market accumulation, completely defines the "gold standard" of MPV industry, and highlights the king’s strength of "the strongest luxury hybrid MPV". (CIS)

Proofreading: William Wang