Fast technology January 19 news, a few days ago, Xiaomi CEO Lei Jun released a video, personally taking everyone to immerse themselves in Xiaomi’s first car Xiaomi SU7.

As you can see,Lei Jun unlocked the vehicle through Xiaomi Watch, and at the same time, the tail wing also rose synchronously, which was very handsome.

After Lei Jun enters Xiaomi SU7 and starts, the main driver’s seat will be automatically adjusted to the memory position. The advantage of this function is that it is convenient to get on and off.

Xiaomi SU7 is also equipped with a dashboard that supports automatic flipping.Support to display total mileage, gear, driving mode and total energy consumption.

Finally, Lei Jun also demonstrated the head-up display function in the car, which can display information such as remaining power, speed and navigation.

The watch is unlocked, the tail wing is automatically raised, the main driver is automatically adjusted, and the dashboard is automatically turned over. It must be said that these processes in one go have already filled the sense of ceremony before Xiaomi SU7 runs.

It is worth mentioning that some netizens sincerely asked Lei Jun in the comment area: Will there be Redmi cars? ".

In this regard, Lei Jun replied: At present, we are still focusing on Xiaomi Automobile. "

It is understood that the first models of Xiaomi SU7 will be equipped with Xiaomi super motors V6 and V6s, with a speed of up to 21,000 rpm, and adopt a new super 800V silicon carbide high-voltage platform developed by Xiaomi, with a maximum voltage of up to 871V V.

(reporting)

　 　 　 　Luo Jing, the host of the famous News Network, Cindy Lee, the actor who plays Fang Yu in Deep Rain, and Fuck off! Tumor jun touched many netizens’ cartoonist Xiong Dun … In recent years, many celebrities have passed away because of lymphoma. At the same time, however, there are also many famous people who have succeeded in fighting cancer after suffering from lymphoma. For example, the 70-year-old famous director Wu Yusen was diagnosed with large B-cell lymphoma in tonsils when filming Taiping Wheel in 2008. After four operations, in the second month of chemotherapy, his mouth was all festered, he could not swallow, and his body and face were so thin that he was wrinkled. Finally, he succeeded in fighting cancer with his firm will! 　

　 　 　 　For example, Kai-Fu Lee, the founder of an innovative factory that successfully used chemotherapy and targeted therapy to fight advanced lymphoma! On September 5, 2013, 52-year-old Kai-fu Lee announced that he had stage IV follicular lymphoma and had to leave work for treatment. In February 2015, he announced the results of his physical examination, indicating that the tumor in the body is not obvious at present. In June of the same year, Kai-fu Lee said that he had not found any lesions in his last two examinations and ridiculed himself as "Li Kangfu". It took Kai-fu Lee less than two years from finding out the cancer until the focus was completely gone. His anti-cancer experience is worth learning from.

Alias "the most disguised disease", lymphoma has become a killer.

　 　 　 　According to statistics, there is a new case of lymphoma every 9 minutes in the world. The incidence of lymphoma in China is 0.02‰, with about 25,000 new patients and nearly 20,000 deaths each year. The threat of lymphoma is rapidly emerging. It ranks among the top ten malignant tumors in China and ranks second among hematological malignancies. At the beginning, the symptoms of the disease were hidden, and it was described as "the most disguised disease". In the intercontinental area, the incidence of non-Hodgkin’s lymphoma is much higher than Hodgkin’s disease, which is about 9: 1. Because of the higher degree of malignancy and worse prognosis, lymphoma is generally referred to as non-Hodgkin’s lymphoma. In China, the incidence of malignant tumors ranks ninth among men and tenth among women. Non-Hodgkin’s lymphoma can occur in all ages, and the high incidence age is 45~60 years old. Among them, Luo Jing suffered from diffuse large B-cell lymphoma (DLBCL). This is a common non-Hodgkin’s lymphoma, which belongs to aggressive lymphoma with high malignancy. The course of the disease progresses rapidly. If it is not actively treated, the median survival time is less than one year. In recent years, great progress has been made in the research and treatment of lymphoma, and new drugs and technologies have risen strongly! CAR-T therapy Among them, the chimeric antigen receptor T(CAR-T) cell therapy is particularly prominent. Its appearance represents a great progress in personalized cancer treatment, especially bringing the hope of rebirth to patients with hematological malignancies.

Complete remission! The first advanced lymphoma patient in China who received CAR-T therapy was discharged smoothly!

　 　 　 　Although they all suffer from diffuse large B-cell lymphoma, Mr. Chen, who suffers from malignant lymphoma, is a lucky one. According to Jiangsu public news channel News Space Station, on August 31st, the first lymphoma patient treated with CAR-T cells in China achieved complete remission and was discharged smoothly. 　

　 　 　 　Mr. Chen suffered from diffuse large B-cell lymphoma. After the onset of the disease in October 2010, he had received chemotherapy for many times, but all of them were unsatisfactory. Diffuse large B-cell lymphoma is the most common malignant lymphoma. After immunotherapy, about 60% patients can survive for a long time, but 40% patients will still relapse. In June this year, Mr. Chen accepted CAR-T cell therapy with a tentative attitude, and all the physical indicators tended to be normal. He told reporters with delight that his physical condition was better than before, and he was no different from a normal person after leaving the hospital. CAR-T therapy, a "living drug", made her completely relieved and looked forward to a cancer-free future.　

　 　 　 　As a "living" drug, CAR-T therapy is very different from traditional drugs. First, the therapy needs to isolate T cells from patients and modify them with chimeric antigen receptor (CAR) in vitro, so that they can specifically recognize cancer cells. Finally, the modified T cells are expanded and reinfused into patients. Compared with traditional chemotherapy and hematopoietic stem cell transplantation, it can kill tumor cells more accurately, improve the curative effect and greatly reduce the side effects. 　

The well-known director of hematology in China said: CAR-T can identify lymphoma very deliberately, and the antigen carried on tumor cells will attack directly after being connected, and it will produce an anti-tumor effect and kill it directly without the need for second signal stimulation, so one of its characteristics is accuracy, and the second is power. The scope of application is still the recurrence or refractory diffuse large B lymphoma that is ineffective in general immunochemotherapy. 　

CAR-T therapy FDA approved 6 models, and domestic CAR-T therapy caught up! 　　　

　 　 　 　After sharing the above news reports about CAR-T therapy, let’s get down to business and talk about CAR-T therapy. At present,CAR-T therapy has achieved great success in the treatment of hematological malignancies.. Six CAR-T cell therapies have been approved by FDA in the United States and two CAR-T cell therapies have been listed in China. The picture below shows CAR-T cell therapy that has been listed at home and abroad. 　 　　

　 　 　 　Although China’s CAR-T technology started late, the domestic market is large. According to the data on Clinicaltrials.gov’s website, China became the country that registered the most CAR-T tests in September 2017. As of May 27th, 2021, there are 1301 CAR-T clinical trials in the world, and the number of CAR-T trials registered in China has reached 478!　

01　　The first CAR-T therapy in China was approved for listing! China welcomes the first year of cellular immunotherapy.

　 　 　 　On June 22nd, the blank in the field of CAR-T in China was finally broken! The latest announcement of China National Medical Products Administration (NMPA), Fosun Kaite Biotechnology Co., Ltd. (hereinafter referred to as " Fosun Kate ”） The CAR-T cell therapy product targeting CD19, Aquilencel Injection (also known as Aquilencel, FKC876), was officially approved for marketing. This is the first approved CAR-T therapy in China and the sixth approved CAR-T therapy in the world. It is believed that China will usher in the blowout era of CAR-T cell therapy.　

02　　In just one month, the second CAR-T therapy in China and the sixth CAR-T therapy in the world were approved!

　 　 　 　On September 3, the State Drug Administration recently announced that Yaoming JunuoThe CAR-T product targeting CD19, Regiosai Injection.(relma-cel, trade name: Benoda) has been officially approved. The approved indications for Regioside Injection are:It can be used to treat relapsed or refractory large B-cell lymphoma (r/r LBCL) in adult patients after second-line or above systemic treatment.Reggiorense injection is the second CAR-T product approved in China and the first CAR-T product of Class 1 biological products in China.

　

It’s only been about one month since it was submitted for examination and approval on July 30th last time, which can be described as rapid progress. Congratulations! (At present, patients with economic conditions can contact cancer-free homes for the treatment of regiorense. )　

Boom! The first BCMA CAR-T therapy in China and the second in the world was approved by FDA!

　 　 　 　China’s "dark horse" in CAR-T cell therapy industry-legendary BCMA(B-cell mature antigen) CAR-T therapy Cedar-B38m/JNJ-4528 (hereinafter referred to as cilta-cel) has attracted much attention, and has shown excellent anticancer activity in clinical trials for multiple myeloma.

　 　 　 　What is exciting is that on February 28th, 2022, local time, it was jointly developed by Janssen and Legendary Biology.BCMA CAR-T product, Cedactylosin (trade name Carvykti), has been approved by the US FDA for the treatment of adult patients with relapsed/refractory multiple myeloma (MM).

This is the first cell therapy product approved by FDA in China and the second CAR-T cell immunotherapy approved for BCMA in the world.

　

　 　 　 　Cilta-cel was awarded priority review qualification by FDA on May 26th.However, the approval of the West Dachiorensai was delayed, and it was adjusted from November 29, 2021 toFebruary 28, 2022Fortunately, it was finally approved and lived up to expectations!

　 　 　 　cilta-celIt is a CAR-T therapy directed by research B cell maturation antigen (BCMA), which is used to treat relapsed or refractory multiple myeloma (RRMM). These patients received an average of five kinds of pre-treatment before treatment, 76% of them received five kinds of treatment, and 86% of them were resistant to five kinds of treatment, including CD38 treatment, and they were both resistant to protease inhibitor PI and immunomodulator IMiD. Simply put, it is refractory to relapse and lack of effective treatment in the follow-up. The principle of this CAR-T therapy is different from the current PD-1/L1. It directly uses the T cells in the patient’s body, transforms them in vitro, replicates them in large quantities, and then transfuses them into the patient’s body to kill cancer cells. At the ASH conference in 2021, the latest results of the 1b/2 CARTITUDE-1 study (n=97) showed that,meso-position 22 months Long-term follow-up, The objective remission rate (ORR) reached 98% , 83% patients achieved strict complete remission (sCR) It is emphasized that the mitigation will deepen with the passage of time (sCR will increase from 67% reported at the ASH annual meeting in 2020 to 83%). At 18 months, 66% of the patients were alive and the disease did not progress. .The two-year progression-free survival rate and overall survival rate are respectively 61% and 74% .The latest research results to be announced at the ASCO annual meeting in 2021 show that After a median follow-up of 18 months, the overall survival (OS) rate was 81%. The remission rate is comparable in all pre-specified subgroups and patients with different treatment lines.

　　 　

American research shows that cilta-cel has excellent long-term efficacy.　 　

　 　 　 　Emily, a foreign country, successfully ushered in nine years of cancer-free survival in 2021, and suddenly became the "spokesperson" of global CAR-T therapy. In China, there is such a lucky person whose fate has been completely changed by CAR-T therapy. Mr. Min was diagnosed with a special rare disease at the age of 54- multiple myeloma . He had no drugs available at that time, so he was lucky enough to participate in the clinical trial of CAR-T therapy. Although the treatment process was not smooth sailing, after three times of treatment, all the lumps on Mr. Min’s body disappeared and the pain disappeared. Surprisingly, by June 4, 2021, Mr. Min had lived cancer-free for five years, which is the field of cancer treatment, which is theoretically said. Clinical cure .

　 　 　 　In fact, as early as March 27th this year,The FDA approved the first CAR-T therapy targeting BCMA for adult patients with relapsed/refractory multiple myeloma (r/r MM) after receiving more than four therapies.

　 　 　 　Chemotherapy to fight cancer is often "killing one thousand enemies and losing eight hundred". Antibody drugs can accurately find tumor targets, but sometimes their combat effectiveness is insufficient. If we can put a "warhead" of chemotherapy drugs on antibody drugs, can we attack cancer cells more accurately? Based on this, an ADC (antibody drug conjugate) called "biological missile" was born. Antibody-coupled drugs are like biological missiles, which consist of two core functions: the first is antibody (missile body), the second is strong chemotherapy drug (nuclear warhead); This design will enable antibodies to find tumor cells with chemotherapy drugs, and then accurately poison tumor cells and poison them. 　This drug design combines the precision of targeted drugs with the high efficiency of chemotherapy drugs, which not only avoids the toxic and side effects of systemic use of chemotherapy drugs, but also has stronger killing ability than using targeted drugs alone, killing two birds with one stone. 　 　 　 　

Schematic diagram of antibody-coupled drugs 　 Note: (a) General description of A)ADC structure; (b) the mechanism of B)ADC. 　

Fourteen ADC drugs have been approved around the world, which brings hope for prolonging the survival time of back-line patients.

　 　 　 　At present, more than 100 kinds of ADC are undergoing clinical trials. Most adcs have progressed from phase i to phase II. Some ADC phase III trials show positive results; Up to September 20th, 2021, there are 14 kinds of ADC drugs on the market in the world, which are mainly used in hematological tumors and solid tumors, and are mainly used for back-line treatment of patients, including advanced, recurrent/refractory and metastatic tumor indications.

　

Fourteen ADC drugs have been approved worldwide.

According to the curative effect data, ADC drugs have brought more treatment options and the hope of prolonging the survival time for back-line patients, and the objective remission rate or median progression-free survival time of several drugs has doubled compared with chemotherapy.

Looking at the CD30 target, the new drug F0002-ADC became an instant hit and squeezed into the lymphoma track.

　 　 　 　CD30, a member of tumor necrosis factor (TNF) receptor superfamily, can promote cell proliferation or apoptosis by activating different signal pathways. In 2020, Vebtuximab for injection (Adcetris) was approved to be listed in China, and CD30 became famous. Adcetris, as an antibody-coupled drug targeting CD30, has an effective rate of 73% for Hodgkin’s lymphoma (HL) and 86% for anaplastic large cell lymphoma (ALCL). It is the first new drug approved in the field of Hodgkin’s lymphoma treatment in recent 30 years, and it is also the first time that a drug targeting CD30 has been approved, filling the gap in this field. At present, the only new ADC drug for CD30 in China is F0002-ADC. This new drug consists of three parts, namely, human-mouse chimeric anti-CD30 monoclonal antibody, thioether linker (MCC) and DM1. Since the project was launched in 2016, it has been disappointing! At present, patients with recurrent/refractory CD30 positive peripheral T-cell lymphoma are being recruited clinically! This is a new treatment option for patients with recurrent/refractory peripheral T-cell lymphoma!

This article is original for a cancer-free home, and it needs authorization to reprint! Cancer-free homes remind patients 　

Mercedes-Benz E-Class is a traditional luxury medium-sized and large-sized car product. For Biao and Audi a6l, its unique brand advantages and extreme luxury attributes have made it deeply recognized by consumers, with an average monthly sales volume of more than 13,000, which is in a strong competitive position in this market segment.

Mercedes-Benz e300l luxury design atmosphere, strong business atmosphere, the front shield-shaped mesh is quite eye-catching, two bar-type led light groups are shiny and recognizable, and the erected three-pointed star logo is also noble and elegant, which can always give people a strong psychological hint. The side is slender and smooth, the lines are smooth and sexy, the rear tail is sexy and stocky, the bilateral double exhaust is quite graded, and the overall face value is remarkable, which is a small S-class.

In terms of power, e300l is equipped with a 2.0t high-powered version, 190 kW, 370 Nm, equipped with a 9-speed manual, with a zero-hundred-speed score of about 6.6 seconds, which makes the acceleration feel smooth and calm at the beginning, and at the same time, the latter part is full of confidence and orderly shift logic, which is always indifferent and comfortable to drive, and can raise the speed to a very high level unconsciously.

In terms of structure, the training style is still very comfortable, the bumps on the road are handled in place, and there is not much impact when taking some bad roads. Driving is particularly heavy and advanced, which will definitely bring people the highest level of enjoyment, which is in line with the level that this level should have.

In terms of selling price, the official guide price of the 2019 Mercedes-Benz e300l Deluxe Edition is 492,800, with a preferential margin of about 40,000. The transaction price of the bare car at the terminal is 452,800, including 40080 purchase tax, 480 travel tax, 950 compulsory insurance, 12,299 commercial insurance and 500 licensed cars, totaling about 507,200.

Car experience:

Most satisfied with fashion and youth, cool atmosphere lights and a sense of science and technology in off the charts! 9-speed automatic transmission, almost no frustration!

The most dissatisfied with the sound effect is just so-so. The original car’s own sound is really lame, not as loud as Berlin’s.

[Space] The space in the front row of my 176 is quite large. There is not much horizontal space for two people. Three people are not very comfortable. From driving to now, I have only gone home for the Spring Festival, and I have been full of company group tours. Basically, I am alone.

[Power] The power is smooth between 234 gears, and occasionally, there will be some setbacks in oil collection.

[Control] Control is general, and this owner plays.

[Comfort] The front seat is comfortable and the rear seat is short.

[Appearance] I bought a sports label with pearl white. I feel very young. In fact, I am already young.

[Interior] Family-style design is adopted, just like driving an S. Due to the hasty booking of a car, the car comes with a black interior, which is a little depressing, but quite resistant to dirt.

[Cost-effective] If people like me don’t pay attention to performance, people who look at their eyes will buy a car of around 500,000, which is still very good.

Provided by the author

On October 24th, after the incident of eyebrow pencil in 79 yuan, the live broadcast room in Li Jiaqi broadcasted Huaxizi with goods again after 43 days. However, Li Jiaqi himself did not appear to explain the product of Huaxizi, and the controversial ace product Huaxizi eyebrow pencil did not appear in the live broadcast list. According to Time Finance, Hua Xizi’s performance in the live broadcast room in Li Jiaqi is still good, but compared with last year, it is much worse.

I and the disputed eyebrow pencil did not appear.

In the list of products with goods in Li Jiaqi Live Studio, there are three products owned by Hua Xizi, namely, a combination suit of 357 yuan, a powder cake of 149 yuan and honey powder of 129 yuan. According to Time Finance, at 8 pm, the live broadcast room in Li Jiaqi exceeded 10 million people. After the countdown was displayed on the screen, the gongs and drums in Li Jiaqi’s hand were sounded, and the pre-sale of Tmall "double 11" officially kicked off this year.

As soon as the live broadcast was started, more than 7,000 pieces, 3,000 pieces and 300 groups of Huaxizi air honey powder, Yurong gauze powder cake and water hibiscus in the Li Jiaqi live broadcast room had been booked respectively. At 8: 02, more than 20,000 pieces, 9,000 pieces and 1,000 pieces of three groups of products were ordered respectively. The figures will change every few minutes. By 10: 30 pm, the pre-sales of the above three groups of products exceeded 70,000, 3,000 and 30,000 respectively. According to Red Net, as of 11: 30 p.m. on 24th, the amount of honey powder with a price of 129 yuan for Huaxizi has exceeded 80,000 orders, the amount of powder cake with a price of 149 yuan has exceeded 30,000 orders, and the combined set with a price of 357 yuan has exceeded 3,000 orders, totaling more than 110,000 orders.

Although Hua Xizi’s performance in the live broadcast room in Li Jiaqi is still good, compared with last year, it is much worse. According to previous media reports, at 9: 00 pm on October 24th, 2022, the colored powder cake of Huaxizi Yurongsha was first released in the live broadcast room in Li Jiaqi. After only 15 minutes on the shelves, 250,000 colored powder cakes were sold out. According to Time Finance’s analysis, in addition to the previous storm, the sales volume of Hua Xizi was affected, and this sales performance may be related to the fact that Hua Xizi did not appear in the prime time of the live broadcast room in Li Jiaqi this year. According to Red Net, as of 11: 30 pm on the 24th, the number of viewers in the live broadcast room in Li Jiaqi was still at 10 million+.

The controversial ace product Hua Xizi eyebrow pencil did not appear in the live broadcast list. According to Time Finance, in the live broadcast room of Huaxi’s official flagship store, the anchor said that the eyebrow pencil "double 11" activity had not been announced. In the live commentary area, some netizens said bluntly: "I will never buy it again, which is really sad" and "How dare he"; However, some netizens said: "Although I am not interested in Hua Xizi, I am still interested in the things in the live broadcast room in Li Jiaqi."

Hua Xizi deeply binds Li Jiaqi.

Earlier, on September 10th, when Li Jiaqi introduced a Huaxizi Eyebrow Pencil in 79 yuan, he saw a message from a netizen saying it was expensive, and replied that 79 yuan Eyebrow Pencil could not be bought because he didn’t work hard enough. At the same time, it was exposed that 79 yuan Eyebrow Pencil was only 0.08 grams more expensive than gold, which led the netizens to think that Li Jiaqi despised ordinary people, created anxiety and inflated commodity prices.

In the early morning of September 11th, Li Jiaqi posted a blog post apologizing, and released an apology video on the evening of the same day, saying that his inappropriate remarks disappointed everyone, and he would also reflect on why he started in the first place and how he could serve more girls. Thank you again for your criticism and supervision. However, many netizens said that they "don’t buy it" for Li Jiaqi’s apology, and joked "Where ‘ Li ’ Wrong? " According to Xinmin Evening News, before the eyebrow pencil incident in 79 yuan, the number of fans in Weibo, Li Jiaqi was 30.435 million. By 11: 00 on October 24th, the number of fans was 28.747 million, and the number of fans dropped by over 1.68 million.

According to the International Finance News, four years ago, Hua Xizi announced Li Jiaqi as the chief recommender of the brand. At that time, this little-known brand was established only two years ago. With the help of the flow of "lipstick brother", the sales of Huaxizi reached 1.13 billion yuan that year, which was 25 times higher than that of 2018. The deep binding between the two parties began in 2019. According to the magic mirror data, the sales of Huaxizi’s star product, carved lipstick, increased by 165% month-on-month after it was promoted by Li Jiaqi multi-platform in May of that year. On the battlefield of "double 11", Hua Xizi never missed the live studio in Li Jiaqi from the pre-sale stage, and with the help of Li Jiaqi’s strong ability to carry goods, he won 220 million yuan GMV for the first time in the war and became the second place in domestic beauty cosmetics.

Around the "double 11" in that year, the live broadcast room in Li Jiaqi contributed 64% of the total turnover of Huaxizi. In June, 2022, Li Jiaqi stopped broadcasting for some reason. During the "June 18th Promotion" period, the sales of Huaxizi, who lost Li Jiaqi, dropped to 150 million yuan from 263 million yuan in the previous year. According to shanghai securities news, the founder of Huaxizi once said in public that their cooperation with Li Jiaqi is Live Delivery 2.0, that is, inviting anchors to create products together. Some insiders revealed: "As long as this product Li Jiaqi says no, it will not pass."

After the eyebrow pencil dispute, Li Jiaqi gradually withdrew

Although Li Jiaqi still has a long way to go to quell doubts and rebuild trust, compared with Hua Xizi who was involved in the storm by his inappropriate remarks, as the starting point of the storm, he seems to have gradually withdrawn from the continuous controversy.

According to previous poster news reports, on September 26th, Li Jiaqi was carrying goods live on Taobao on the night when Hua Xizi’s crazy public relations sparked heated discussion. At the beginning of the storm, a large number of netizens flocked to the live broadcast room in Li Jiaqi to denounce it. Then, there were few questioning voices in the comment area, and the live broadcast room seemed to have returned to its former order. At 21: 42 on September 26th, the poster journalist entered the Taobao live room in Li Jiaqi, when he was carrying lipstick of Mao Geping brand, and the number of viewers in the live room was 7.146 million.

According to the International Finance News, the third season of the self-made variety "All Girls’ OFFER" produced by US ONE arrived as scheduled, showing the process of "negotiation" between Li Jiaqi and major beauty brands, which greatly promoted the upcoming "double 11". Janice (pseudonym), a well-known MCN organization engaged in beauty cosmetics vertical operation, said in an interview with the International Finance News that the Li Jiaqi incident had no impact on her MCN organization. "No matter what, the brand will still come to us for cooperation."

An insider of ONE told reporters that after the incident, the company’s publicity scale during the "double 11" period may be reduced, but "the traffic brought by the live broadcast room in Li Jiaqi is still very large." It is blunt that in the past few years, US ONE has established a large-scale system from product selection to after-sales improvement, and it still has advantages in the field of live e-commerce. "Especially after public relations, the trend of public opinion has become ‘ I don’t care about the anchor, anyway, as a consumer, it is good to buy a cheap and cost-effective product ’ 。” However, in the view of Wang Tian (pseudonym), a business practitioner of a live broadcast room in online celebrity, Tik Tok, if the live broadcast room in Li Jiaqi accounts for a large proportion of the brand’s performance planning of Taobao platform, after the storm, the brand may avoid risks by reducing the frequency of cooperation with Li Jiaqi and increasing the number of people to broadcast. "In the long run, the brand will expand other options besides super anchor. They also have their own plans and will not bet on one person. "

Upstream news is integrated from The Paper, Xinmin Evening News, International Finance News, Red Net, shanghai securities news, etc.

From Chen Kun to Roy and Karry, among the stars who are constantly "harvesting" attention in the entertainment circle, it seems that there is never a lack of Chongqing elements. If it is said that ten years ago, Chen Kun began to impress the audience with his youthful and immature acting skills, it was the beginning of Chongqing children’s journey in the entertainment circle; Then at the dawn of the second decade of the new century, successors have appeared on this long journey …

Needless to say, Roy and Karry, two children who have long been popular all over the country through TFBOYS, Sean Xiao, who won the popularity of the new generation of actors this year, Vin, Ivan and YoRoll , who are the most popular new men’s team at present, followed closely, and J.zen, Gu Landi and other names have repeatedly refreshed your understanding of the newcomers in the entertainment circle. In the next decade, it should be the following new forces that attract your attention and guide your remote control and mouse.

Sean Xiao

The hottest Chinese actor this year

How new is the "new power"? We might as well take the year 2000, the first year of the 21st century, as the base point.

That year, Chen Kun was a student of the Beijing Film Academy. After the movie "National Anthem", he participated in his second drama "Like Fog, Like Rain and Like Wind", but at this time he was just a little coffee hidden behind the highlights of Zhou Xun and Lu Yi. This year, Roy and Vin were born, Karry just turned one year old and YoRoll  and Ivan were two years old. The older ones are J.zen and Gu Landi, who are 5 and 6 years old respectively. Xiao Zhan, who is 9 years old, should start learning piano under the guidance of his father.

Wei Wuxian played by Sean Xiao The Untamed.

In a blink of an eye, 10 years later, they all became "popular fried chicken", and some of them were even hotter than Chen Kun in 2000.

If you want to ask how hot Sean Xiao is now? Just pay a little attention to the frequency of his name appearing in various news information in the last week, and you can perceive one or two. New Year’s Eve and New Year’s Day are approaching. He is on the guest lists of CCTV, Beijing Satellite TV and Oriental TV. Among them, Beijing Satellite TV also chose Sean Xiao as the spokesperson for the 2020 Spring Festival Gala.

Sean Xiao became the spokesperson for the 2020 Beijing Spring Festival Evening.

Not only that, all kinds of "harvest" hot search and attention in Sean Xiao can be described as full bloom. Let’s take a closer look at the variety field. In the music reality show "The Voice of Chinese Dreams Our Songs", which is being broadcasted by Oriental TV, his partner, Tian Na Ying, praised him as "really handsome" from the first sight, and the following two people’s cooperation, "Follow Your Feelings" and "Night at the Naval Port" were hotly debated in every capital.

Sean Xiao has become the "darling" of fashion magazines.

Secondly, magazine covers and photos, which have always been Vogue of the main battlefields for star competition, have ELLE published Sean Xiao’s photos or covers.

In the field of TV series, The Untamed, a costume drama that was popular all over the network in June this year, was regarded as the tipping point of Sean Xiao’s popularity. In the play, his handsome appearance is just in line with the audience’s imagination of Wei, the original character: clean, optimistic and cheerful. On December 20th, Douban made a ranking list from movies to TV series in 2019. The Untamed ranked third in the highest-rated Chinese drama series in 2019 with 8.3 points, and Sean Xiao won the first place among the most watched Chinese actors in 2019.

Sean Xiao in college.

Compared with several Chongqing babies who will be mentioned later in Ran Ran, Sean Xiao is not too young. Born in 1991, he studied painting, violin and other literary specialties under the cultivation of his father since childhood. In 2010, Sean Xiao was admitted to chongqing technology and business university Modern International Design and Art Institute. Since he entered the school, he has been a member of the class’s literary and art committee, and also served as the head of vocal music department and male voice department of the college students’ art troupe, as well as an actor of the school’s language and art sub-group.

In her sophomore year, Sean Xiao, who won the title of "Top Ten Singers on Campus" in chongqing technology and business university, participated in the "Top Ten Singers on Campus" competition in Chongqing on behalf of her school and won the second prize. It is worth mentioning that when he was a student, Sean Xiao also played a lot of tricks in his professional field: in 2012, he and his friend Camera founded the "Recalling Light and Shadow Visual Media" photography studio and the "NED Design Studio", and he was the main photographer and designer.

Until now, Weibo’s name in Sean Xiao still retains the head of his newly-debuted group "X-Nine Youth League". In June 2015, he was invited to participate in Zhejiang Satellite TV’s amateur inspirational program "Burn Boys" and became a trainee. In the finals in February of the following year, although Sean Xiao and his teammates narrowly lost to the Chris Lee team, in September of the same year, they announced their debut as the lead singer of the X-Nine Youth League. Since then, Sean Xiao’s performances in costume dramas "Breaking the Sky" and "Your Highness the Wolf" have been recognized by everyone. In the popular costume drama Joy of Life, although Sean Xiao is a supporting role, the hot discussion expected by netizens has spread all over the network since the first day of the drama.

Up to now, the number of Weibo fans in Sean Xiao has reached a staggering 21 million, and among the more than 700 Weibo posts, the likes of any one easily exceeded 1 million. It is no exaggeration to say that, as Douban commented, he is definitely the first most concerned Chinese actor at present.

The hottest new men’s team "R1SE"

Three of the 11 members are Chongqing children.

R1SE men’s team

On 14th of this month, R1SE, a men’s group, announced that it had been a group debut for less than half a year, put "WE ARE R.1.S.E-2019 R1SE National Tour Concert" into the Chongqing Concert of Chongqing Huaxi International Cultural and Sports Center. The scene is naturally screaming and cheering. This concert is of great significance to the three members of R1SE: Vin, Ivan and Zhang Yanquan are authentic Chongqing babies.

For this reason, R1SE specially designed an interactive session with unique regional characteristics for Chongqing fans. The members not only adapted the lyrics of the song "Deba" into Chongqing dialect "Yaode", but also performed a dialect chorus with the live fans. Combined with Chongqing special hot pot, a creative game "What’s in the hot pot restaurant" was created, which made the concert scene burst into laughter again and again.

Back in June this year, the reality show "Creation Camp 2019" launched by Tencent Video specially selected men’s teams finally scheduled the final seats. According to the program rules, 11 members of the "R1SE" group who made their debut as a group were born. Among the 11 members born after the elimination of 101 trainees, three Chongqing children were included: the names of Vin, Ivan and YoRoll  instantly became popular on the Internet.

Vin

You are not mistaken. After 00, you have already started to board this eye-catching stage. Vin, the third of the three, was born in 2000, while YoRoll  and Yao Chen were both born in 1998. According to Vin’s self-report when he participated in Creation Camp 2019, his idea of going on stage was influenced by Michael Jackson: in 2012, at the age of 12, after watching Michael Jackson’s performance in This is it, he had the idea of going on stage for the first time, and it got out of hand. He first signed up for a street dance class, and then spent two years persuading his parents to let him take the road of acting. Before participating in the domestic draft variety show, he went to an entertainment company in South Korea as a trainee in 2014.

Before this year’s "Creation Camp 2109" won the C place, Vin had already won the fourth place in the 2017 musical idol cultivation program "Son of Tomorrow" and made her debut. Two months ago, Vin was selected into the 2019 Forbes China list of 30 elites under the age of 30 by virtue of her popularity.

Ivan Yao

Ivan, born in 1998, also had the experience of joining a Korean entertainment company as an intern. In "Creation Camp 2019", Yao Chen’s first stage performance of "Baddd" attracted countless attention. During the performance, Ivan inadvertently lifted his T-shirt to reveal eight abdominal muscles, which also made him known as a "small waist" by fans.

YoRoll 

YoRoll  is famous for her "interesting soul" among R1SE members. On the one hand, he keeps making golden sentences in the "Creation Camp 2019" program, such as calling PK among students "mutual torture to the bald head"; On the other hand, the scene of Chongqing Xiaoer, who is super spicy, recommending Laoganma’s hot sauce for other students in the program has also made fans talk about it for a long time.

The scene of YoRoll ‘s crazy recommendation of hot sauce

As he himself said in the program, his interest in rap began in junior high school. "My classmates showed me a rough MV made by a domestic rapper, but the content was very close to life." He immediately fell in love with this form of writing everything that happened around him into a song and began to try originality. Nowadays, family members are very supportive of this road chosen by Zhang Yan. In an interview, he even laughed that his father is his number one male fan. "His ten circle of friends, nine of them are all about me, and I find people everywhere to like me."

J.zen

A cold folded ear root was forwarded by Weibo for more than 240,000 times.

On December 22nd, J.zen’s name was posted on the hot search because Ronghao Li, who had just finished his concert in Chongqing, met Xiao Zhu at the airport and stopped him. At first, he didn’t react. When he recognized that he was Ronghao Li, the music tutor when he participated in the online comprehensive Idol Trainee, J.zen’s appearance as a good student made fans happy instantly.

J.zen

If you don’t know J.zen, it only means that you are either old or Out.

Now logging in to Luneng Bashu Middle School, official website can find J.zen’s name in the classmate record of Class 16, Grade 2012.

J.zen was born in Chongqing in 1994. Until now, if you log in to Luneng Bashu Middle School, official website can find his name in the previous student lists. He is in Class 16, Grade 2012. Compared with Chongqing’s fellow villagers who are equally popular in the entertainment circle today, J.zen is a broader type. He and Variety should have been electrocuted since high school: in 2011, J.zen’s name was included in the second season of China’s Got Talent. Later, he entered Beijing Modern Music Institute to study in university.

The reason why J.zen dabbles in a lot is that he has appeared in the dance competition program, the magic reality show and the most popular variety show "Hip-hop in China" in 2017 (entering the top 46 in China). However, if we really want to say that J.zen’s name is on fire, it is inseparable from the reality show "Idol Trainee" formed by the idol men’s team that was red and purple last year. In this program, J.zen and the current traffic took the PK of KUN, Chen Linong and Adam, and finally ranked 14th. This achievement is quite rare.

This year’s Spring Festival, J.zen’s cold salad is broken.

How hot is J.zen, who has released his second personal music EP "Something Worth mentioning" in April this year? The reporter noticed that the number of his real-name authentication fans in Weibo has already exceeded 6.4 million. As a Chongqing cub, he is naturally unambiguous in eating. Apart from basking in the Vlog that he made "Chongqing tomato scrambled eggs" and "boiled meat slices", this year’s Spring Festival J.zen basked in a picture of himself eating New Year’s Eve dinner at home in Chongqing: "The legendary braised fish of grandma and the broken ears of grandpa’s cold salad". This Weibo has been forwarded more than 240,000 times, and the number of likes has exceeded 78,000 times.

Gulandi

Chongqing guy who won the popularity of "making stars in a new way"

Compared with his peers in other circles, Gu Landi, who was born in Chongqing in 1995, was quite unconventional from his debut to his popularity. Although he also participated in Iqiyi’s talent show "Youth has You", he actually made his debut before this program started: In the online drama "Love You So Sweet" of Tencent video last year, Gu Landi starred in the male No.2.

Gulandi

In January of this year, Youth with You, which has been regarded as the second season of Idol Trainee, was launched, and Gu Landi joined it as a trainee. After two months of competition, Gu Landi regretted stopping in the top 20, and something interesting happened at this time. He, together with Shi Mingze, Hu Wenxuan, Xu Bingchao and Ding Feijun, formed a men’s team named "D5, the fifth son of the desert" and announced his debut. The operation team behind it is Lehua Entertainment, which has previously launched the "NEXT of the Seven sons of Lehua" (the main members include THEO and Adam).

Displaying the Imperial Capital of Valley Blue is a "trainee" from Youth with You.

The key to saying that it is the result of the current "new game of making stars" is that "the fifth son of the desert D5" announced its existence for only three months at the same time from the date of its birth. Not only that, the unique significance of "Five Sons of the Desert D5" is that it is the first case of spontaneous group cooperation between artists from different companies. People in the industry generally believe that this has unlocked the new mode of idol draft, given the eliminated players new opportunities, and maintained the heat of the players after the game to a certain extent. At the same time of forming a group, "Desert Wuzi D5" has an official fan club, and the membership card valid for three months costs 99 yuan.

During the three-month existence of "Five Sons of the Desert D5", they released two singles successively, and they also appeared in the theme concert of "Burning Snow" in the 1000-day countdown to the Beijing Winter Olympics.

Upstream News chongqing morning post Reporter Qiu Jinxi

[Disclaimer] The texts, pictures, audio and video that are not marked with "Source: Upstream News-chongqing morning post" or "Upstream News LOGO" on the upstream news client are all reposted. If the reposted manuscript involves copyright issues, please contact the upstream news.

1905 movie network news Jumanji: The Next Level, a Hollywood action adventure masterpiece, will be released nationwide on December 6th, and the Brave Team led by "Stonestone" Qiang Sen will be assembled again. This time, the game world is completely out of control, the difficulty of the level is soaring, the visual wonders are escalating, and the lives of four people are hanging by a thread at any time.

On December 5th, the film released a special edition of "All-round Advanced", in which all the main creators appeared to show the interesting shooting process of the film, and all the people worked together to create higher-level works, which perfectly explained the spirit of the brave to challenge the peak. The film is directed by jack Kasdan, and Dwayne Douglas Johnson, Jack Black, kevin hart and Karen Sheila Gillan will return to the whole lineup.

The main creative staff appeared in the comprehensive advanced special edition. 　

Qi Xin, the brave, works together to fight the peak again.

In addition to the thrilling and funny clips of the film, the special edition also exposed the behind-the-scenes shooting tidbits for the first time, and the main creative staff made an appearance to tell about their expectations for the film. Qiang Sen, as the leading actor and producer, has very high requirements for this film: "If you are lucky enough to make a film as successful as the first Brave Game, you must get an by going up one flight of stairs when making a sequel."

For director jack Kasdan, he also wants to "fight the peak again": "We want to challenge ourselves and do something new that was not in the first movie." In order to present a fully upgraded game world, they challenged infinite possibilities during this shooting. Not only were the scenes more diverse and grand, but the actors also went beyond their physical limits.

The reunion of the whole excellent team inspired everyone’s creative inspiration, produced wonderful chemical effects, and created a series of jokes at the same time. For example, Qiang Sen played Grandpa Eddie, which made Awkwafina, who played a mysterious new role, very amazed. In addition, Dr. Yong Shi also met a more powerful opponent — — You Ergen, the cruel man, makes people wonder how the brave will fight against this "ultimate enemy".

"Man-Bird Wars" and "Speeding Cars" are frightening.　

Mouth gun partners love each other and kill each other, which brings laughter again and again　

The brave game world, which has returned to the audience’s field of vision, has ushered in a dangerous escalation and total loss of control, and the rapid transformation of a number of extremely thrilling new levels is dizzying. In addition to the primitive jungle where the man-eating hippopotamus is hidden in the previous work, there are endless abyss that kills people at any time, numerous peak forest pontoons besieged by wild mandrels, extremely cold snow-capped mountains that suddenly collapse and crack, and uninhabited desert & HELIP; …

The wild animals in the game world, such as wild mandrills, angry ostriches, man-eating pythons and ferocious hyenas, are lifelike and terrible, with clear hair expressions and 100% reduction; The ostrich gallops as if it were there, and the flying stones and gravel seem to be in front of it. The immersive visual experience brings the extreme stimulation that makes people’s adrenal glands soar.

At the same time, there are a lot of jokes in the film. Whether Qiang Sen plays a bad-tempered grandfather or kevin hart turns into an elegant old gentleman who speaks very slowly, Gao Fancha’s "laughter" is hilarious, and the two of them start the mode of love and killing each other along the way, which makes people laugh hysterically. In addition, the brave fought fiercely with the angry ostrich brigade and fought side by side with Bethany who turned into a dark horse. The super-burning group battle was exciting and full of jokes. It was a rare "effective" and funny masterpiece.

Global word-of-mouth harvest received rave reviews.　

"The biggest surprise of the year" triggered the expectation of the whole people.

"Jumanji: The Next Level" has been praised by the media since it was announced. Recently, it has been released in other regions and countries, and it has received numerous praises. As a sequel to Super IP, people feel full of sincerity: "It’s great to see such a wonderful sequel!" "Surprise, amazing! After reading it, I look forward to the follow-up development of IP. ""The most surprising, thrilling and sincere Hollywood action adventure blockbuster in 2019 "; The comprehensive upgrade of the visual spectacle is amazing: "This brave game world presents us with a shocking spectacle";

The wonderful performances of the leading actors won numerous praises: "The best partner of Qiang Sen and kevin hart is worth watching, and Awkwafina has excellent acting skills." "I can’t choose the best actor, because everyone in it performed super brilliantly, which makes people sincerely admire!" ; The film brings you thrilling and hilarious sensory enjoyment: "The film has brought me unexpected excitement and continuous laughter, which is simply a surprise everywhere!" The strong word-of-mouth given by local media and audiences has ignited the strong expectations of domestic fans for film release.

Short-listed for the Oscar for Best Visual Effects 　

Top production team to create "the most powerful film in the same file"

Recently, "Jumanji: The Next Level" was shortlisted for the Oscar for Best Visual Effects Award. The shocking visual effects presented in the preview attracted countless audiences, thanks to the top behind-the-scenes production team: more than 5,000 visual effects teams from all over the world created vivid details of fierce beasts;

Spectacular scenes and checkpoints full of imagination are manipulated by artists who have participated in special effects blockbusters; The Oscar-level visual effects director who participated in the production also participated in the production of this film, presenting the imaginary game world realistically and satisfying the dreams of countless people to enter the game world. Since the pre-sale of the film started last week, so far, the pre-sale box office has exceeded 10 million, and the pre-sale ratio ranks first, and other indicators such as wanting to see also take advantage, crushing the films released in the same file.

No matter from the aspects of IP popularity, production level, card lineup, etc., it can be called the strongest giant system at the end of the year. Newly upgraded levels and newly joined characters will present a novel and interesting sensory experience for everyone, which is definitely worthy of the title of the most anticipated Hollywood action adventure blockbuster at the end of the year.

Jumanji: The Next Level, a Hollywood action adventure masterpiece, is directed by jack Kasdan, and the four leading characters, Dr. Yong Shi Dwayne Douglas Johnson, geologist Jack Black, linguist kevin hart and sexy girl Karen Sheila Gillan, will return to the whole lineup! In order to save their lost companions, the Brave Four assembled again and entered an unknown world that was completely out of control. Facing the dangerous barrier of off the charts, Qiang Sen led the team to challenge the limit to escape. An adventure full of thrills and surprises is about to begin.

Everyone knows that Tik Tok is very popular, and live broadcast with goods can make money. Do you know about online celebrity, an e-commerce company in Tik Tok? Let’s take a look at Tik Tok’s ranking of online celebrity with goods together with Xiaobian.

In 2019, Tik Tok is still actively promoting the realization of e-commerce in Tik Tok. Following the list of good things in Tik Tok, Tik Tok officially launched the list of sales of talents recently, which has become the focus of Tik Tok operators. At present, the most popular people who carry goods in Tik Tok are: pomelo cici sauce, Li Jiaqi, Natiguli, Hao Fan, Ye Gongzi, Spicy Lai, good geophysicist and so on.

Even during the epidemic, many cities and roads were closed; However, the live broadcast of Devil Li Jiaqi was repeated after the festival. The live broadcast lasted for 3 hours, watched by 1,600 w+people, with 26,000 boxes of snail powder, 300,000 packs of washcloths and 150,000 bottles of Red Earth liquid foundation, all in seconds. Li Jiaqi, a lipstick brother, revealed in an interview that since January 2019, he has already entered 7 figures in a month by bringing goods through live broadcast;

Undoubtedly, live broadcast with goods has become a popular fried chicken for "selling goods". Live broadcast’s unique timely interaction, hunger marketing, transparent consumption scenes and all-round sensory impact make live broadcast with goods effectively promote the conversion rate and turnover of e-commerce and improve the efficiency of traffic realization.

Interesting content+real-time two-way interaction+the lowest price of the whole network+trust guarantee, and the consumer demand of users is stimulated.

Live broadcast helps e-commerce to change from "goods and people" to "people", and the relationship between anchors, goods and consumers is getting closer and closer.

The anchor sells people and explains to users, and users pay attention to and understand the products because they like an anchor, which enhances the exposure of products and then stimulates the purchase behavior.

The above is the 18183 Xiaobian’s ranking of Tik Tok e-commerce in online celebrity and Tik Tok in online celebrity. I hope it will help you.

Long-term recruitment of anchors: male or female, cheerful personality, talent and expertise are preferred, and network hosting experience is preferred. Novice Xiaobai can also do it. The company provides free training and arranges the live broadcast time and content according to personal ability. The strength of the company supports the application for anchor popularity and ensures the traffic in the live broadcast room.

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Tik Tok dry goods

Why should the guild be added to the live broadcast?

Want to realize short video? Add MCN!

　　□ Our reporter Luo Shasha □ Our correspondent Ding Jin

　　In recent years, with the continuous development of the e-sports industry, some lawless elements have set their eyes on e-sports and surrounding derivative projects in order to gain high illegal interests. A 14-member criminal gang headed by Gong and Liu set up an e-sports company, developed an e-sports game App, and opened a casino in the name of "Bounty Tournament". In just three months, the gambling money involved was as high as 8.6 million yuan.

　　On June 14th, 2023, the People’s Procuratorate of gusu district, Suzhou City, Jiangsu Province filed a public prosecution, and the court sentenced 14 people, including Gong, Liu, Deng and Li, to prison terms ranging from five years and three months to one year and six months, and fined them ranging from 50,000 yuan to 20,000 yuan. Some of them were suspended. He was ordered to withdraw more than 1 million yuan of illegal income and confiscated more than 100 tools such as computers and mobile phones. At present, the judgment has come into effect.

　　In August, 2021, Xiao Liu, a college student who lives in gusu district, Suzhou, got a short live video of "Bounty Tournament". According to the anchor, this game App called "Meet Me" contains all kinds of popular mobile games. If you win in the random pairing game, you can win the bonus, and you can withdraw it through the App.

　　Not only can you play games, but you can also get money if you win? Xiao Liu, who was very excited, quickly downloaded, registered and logged in, and found that to participate in the "prize-winning battle", he had to recharge the diamond in the App as an "admission fee". Xiao Liu has recharged 100 diamonds and transferred to the entrance of a shooting mobile game that he often plays through the platform to participate in the battle. The so-called "bonus" is the sum of the "admission fees" of him and other players. Although he won 100 diamonds in the end, 30 diamonds were automatically taken away by the platform. Under the reminder of a friend, Xiao Liu realized that the platform was involved in gambling, so he immediately uninstalled the App and called 110.

　　After receiving the report, the public security organ filed a case for investigation. The police found that Xiao Liu’s recharge funds flowed to an e-sports company in Chengdu, and a total of 14 suspects including the company’s head Gong, management Liu, App development and promotion and financial personnel were locked up. In September 2021, with the cooperation of the Chengdu police, the police arrested all the suspects and brought them to justice, and the "Mutual Help" App was immediately forced to stop.

　　After investigation, Gong and his friend Liu partnered to open a network technology company, which faced losses due to poor operation. One day, when Gong accidentally saw an e-sports game advertisement of "winning the game and earning a bonus", he wanted to develop an App to explode the popularity of mobile games and use the "bonus" gimmick to attract traffic. The company only needed to sit and enjoy the draw.

　　Later, Gong persuaded five people, including Liu, to use the state’s support policies for the e-sports industry to register and establish Encounter E-sports Co., Ltd. and obtain the e-sports business license. The business scope includes sports competition organization, animation game development, sports event planning and other e-sports related content. Gong is the actual controller of the company, and Liu and other five people are the shareholders of the company. After joint discussion, they instructed five technicians, including Li and Ma, to develop the "Mutual Help" App, which was officially launched in June 2021. The company’s employees, Deng Mou and Huang Mou, used the online platform to promote the "Bounty Tournament" as a gimmick to attract players to download the App. After registration, they recharged through WeChat and Alipay and bought diamonds as virtual coins. After the user pays the prescribed equivalent virtual currency, the platform randomly pairs into the game, and the winner wins all the rewards and cashes out through App. The company draws profits according to the proportion of shooting mobile games 30% and pushing tower mobile games 20%, and financial staff Xu is responsible for fund settlement. After verification, the App has been in operation for 3 months, and the registered users have reached 2.6 million, and the user’s recharge amount has exceeded 10 million yuan.

　　In November 2021, six management personnel, including Gong Mou and Liu Mou, were arrested by the gusu district Procuratorate on suspicion of opening a casino, and eight technical, promotion and financial personnel, including Li Mou, Deng Mou and Xu Mou, were criminally compulsory on bail pending trial. It was found through trial that from June to September, 2021, 14 people, including Gong and Liu, organized players to participate in online gambling through App. The gambling money involved was as high as 8.6 million yuan, and the profit from it was more than 1 million yuan, which constituted the crime of opening a casino.

　　"The company has a legal e-sports license, ‘ Meet each other ’ App is similar to JJ landlord, how can it be regarded as opening a casino? " In January 2022, the case was transferred for review and prosecution. Gong and Liu tried to cover up the facts of the crime and insisted that they were engaged in legal and compliant e-sports business.

　　According to the review of the procuratorate, the "Mutual Encounter Help" App provides users with a recharge channel for converting cash into virtual currency and a withdrawal channel for converting virtual currency into money again. Users can bet virtual currency as a chip, and the companies involved are drawn from the amount bet by each game player. The resulting user recharge and withdrawal are drawn from the companies involved, which correspond to the "up and down" links of gambling respectively, and belong to online gambling activities.

　　"In fact, as long as it meets ‘ Money goes in and money goes out, winning or losing is random ’ This gambling feature can constitute the crime of opening a casino, ‘ E-sports ’ Camouflage is just self-deception. " Undertaking the introduction of prosecutor Liu Ben. In fact, along with the bloody e-sports competition, there were criminals who developed the e-sports quiz App, which allowed players to recharge and bet, and the platform settled and cashed out. In essence, it opened an online casino under the banner of e-sports quiz, which once attracted many players to indulge in it. In contrast, the "mutual encounter" App uses "playing games and winning bounty" as a cover and puts on a "legal coat", which is more confusing and tempting. Young people who love e-sports games, especially students at school, have weak discrimination ability, and are easy to fall into this kind of well-disguised trap, breaking the law without knowing it, so we should take a warning and be vigilant.

　　How can we stay away from this kind of online gambling trap? The procuratorate reminded that buying chips to bet, winning or losing determines the income and can be exchanged for cash. As long as these three characteristics are met, whether it is chess, mobile games or other forms, it is already suspected of gambling violations. The masses must improve their discriminating ability, put an end to luck, download and log in games through official platforms and formal channels, don’t trust online advertisements and private recommendations, and don’t click on links that come from unknown sources. Once illegal activities such as gambling are found, they should take the initiative to refuse and report them immediately. Never believe gimmicks such as "generous bonuses" and "one-second cash withdrawal", otherwise they may be bankrupt, heavily in debt, and may be investigated for legal responsibility.

On November 1st, in the final round of the second stage (Group B) of the Asian Women’s Football Qualifier for the Paris Olympic Games, China drew 1-1 with South Korea, and failed to advance to the Paris Olympic Games.

On November 1st, China coach Shui Qingxia (former) led the players to greet the audience after the game. Xinhua News Agency reporter Jiang Kehong photo

On November 1st, China team player Wang Shanshan (right) struggled in the competition. Xinhua News Agency reporter Wei Peiquan photo

On November 1st, China team player Zhang Linyan (second from left) broke through with the ball in the game. Xinhua News Agency reporter Jiang Kehong photo

On November 1st, China team player Yang Lina cried after the game. Xinhua News Agency reporter Wei Peiquan photo

Source: Xinhua News Agency

Q:What are the nutrition and health problems of Shanghai residents?

A:It is not eating too much, but the dietary structure is unreasonable, mainly because there are less plant foods (cereals/vegetables/fruits) and more animal foods (livestock and poultry meat); The proportion of fat in diet is high, and the energy provided by fat is 38.0%, which exceeds the recommended upper limit of 30%.

First, the problem of overweight and obesity is prominent. As far as diet is concerned, the problem is unreasonable dietary structure (more animal food/less plant food, high fat ratio).

The overweight and obesity rate of Shanghai residents is 44.1%, which is close to the average level of cities in the national nutrition monitoring results from 2010 to 2013 (the overweight and obesity rate of big cities in China is 47.8%). Shanghai residents don’t eat too much. The energy intake of Shanghai residents is lower than that of 10 years ago, which may be related to the change of lifestyle, people no longer engaged in manual labor, and the decrease of energy demand, as well as the trend of energy intake of people found in international and our country’s nutrition monitoring.

There are many factors that cause obesity. As far as dietary factors are concerned, the main problem of Shanghai residents is the unreasonable dietary structure. The traditional Chinese diet mainly takes plant food (cereal is the staple food), which is rich in dietary fiber, which is beneficial to prevent chronic diseases. However, current monitoring shows that the intake of animal food in residents’ diet greatly exceeds the recommended level, while the intake of cereal has dropped significantly in the past 10 years, and the intake of vegetables and fruits is insufficient. Such a dietary structure contains less dietary fiber, which is not conducive to the prevention of chronic diseases. At the same time, the absorption rate of different foods in the human body is different. The current dietary structure may increase the absorption rate of food, which may lead to the increase in the overweight and obesity rate of residents.

On the other hand, the monitoring also found that the percentage of energy provided by residents’ fat was 38.0%, which was close to the average level of big cities (37.2%) in the national nutrition monitoring results from 2010 to 2013. In the recommendation of Dietary Guidelines for China Residents, the percentage of energy provided by dietary fat does not exceed 30%, which has now exceeded the upper limit by a lot. Animal foods, especially livestock and poultry meat, contain more saturated fat. The monitoring results show that the intake of livestock and poultry meat in Shanghai residents’ animal foods exceeds the recommended 61%.

Second, suggestions on unreasonable dietary structure: increase plant food, reduce animal food, and replace some livestock and poultry meat with aquatic products.

1. Increase the intake of plant foods such as cereals, vegetables and fruits.

In view of the dietary nutrition problems found by monitoring, it is suggested that residents gradually improve their dietary structure and increase the intake of plant foods such as coarse grains, vegetables and fruits. Usually, people’s food intake in a day is relatively stable. If the intake of plant food increases, the intake of animal food will decrease accordingly.

It is worth noting that in the past 10 years, the grain intake has dropped significantly. At present, the grain intake of residents is 189.6g, which only reaches 69% of the recommended intake (the recommended intake is 200-300g, compared with 275g/2200kcal). It is suggested that residents should increase the intake of cereals, and at the same time, they should match the thickness, and pay attention to increasing whole grains and miscellaneous beans, because cereals with high processing precision will cause high blood sugar response. Rice can be eaten with whole grains (brown rice), miscellaneous grains (oats, millet, buckwheat, corn, etc.) and miscellaneous beans (red beans, mung beans, kidney beans, flower beans, etc.).

2. Reduce animal food, you can choose aquatic products to replace some livestock and poultry meat.

At the same time, it advocates food diversification. In view of the problem of excessive intake of livestock and poultry meat by Shanghai residents, it is recommended that residents can choose aquatic products to replace some livestock and poultry meat. Livestock and poultry meat contains saturated fat, which is a risk factor for cardiovascular diseases and tumors. Aquatic products contain unsaturated fat, which is beneficial to health.

Finally, it is recommended to choose at least 12 different foods every day to prevent the risk of chronic diseases caused by possible nutritional deficiency or excess.

Third, the rising trend of overweight and obesity among students has not been curbed, and sugary drinks are widely consumed. Excessive drinking of sugary drinks is one of the risk factors of overweight and obesity, so it is suggested that students should be controlled to drink sugary drinks.

There are many factors that cause overweight and obesity, except the unreasonable dietary structure mentioned just now. In addition, there are differences between primary and secondary school students and adults. This monitoring found that it is common for primary and secondary school students to drink sugary drinks. 74.6% primary and middle school students drink sugary drinks more than once a week, and 36.5% primary and middle school students often drink them. It is more common for high school students to drink sugary drinks, and 62.5% of them often drink them. There are also a few students who drink sugary drinks every day. 20.9% of primary and secondary school students drink sugary drinks more than once a day, and the proportion of high school students is even higher. There are 41.5% of high school students who drink sugary drinks more than once a day.

The Dietary Guidelines for China Residents (2016 Edition) recommends that children and adolescents prefer boiled water to sugary drinks every day. Drinking sugary drinks does not produce satiety, resulting in excessive intake of sugar and energy. According to literature reports, excessive intake of sugary drinks can easily lead to various diseases such as obesity, diabetes, metabolic syndrome and blood lipid problems.

It is suggested that primary and secondary school students should be restricted from drinking sugary drinks, students should be encouraged not to drink sugary drinks, and extra sugar and energy intake should be reduced. Parents and school teachers should be aware of the influence of sugary drinks on children’s overweight and obesity. It is suggested that schools should encourage students not to bring sugary drinks into school, schools should not provide sugary drinks for sale, and widely carry out health knowledge propaganda on restricting sugary drinks in schools.

4. The intake of oil and salt in Shanghai has obviously decreased in recent 10 years, thanks to the measures to control oil and salt in Shanghai, but the current intake of oil and salt is still higher than the recommended level, and it is necessary to continue to strengthen intervention.

Our diet is mainly salty, and frying, frying and frying are common cooking methods. Excessive intake of cooking oil and salt in the diet is one of the important factors causing hyperlipidemia and hypertension. According to the monitoring results, the daily per capita intake of cooking oil and salt is 36.4g and 7.5g, respectively, which are 21% and 24% lower than the survey data 10 years ago, and 11% and 16% lower than the national average of big cities.

We compared the trend of oil and salt intake in Shanghai in recent 10 years, and found that it was obviously decreasing. At the same time, we also looked at the trend of oil and salt intake in urban areas of China in recent 10 years, but there was no obvious downward or upward trend, and it remained basically stable. This difference in trend should be attributed to the health education and intervention on oil and salt control led by the Shanghai Municipal Government in the past 10 years, such as the distribution of "salt control spoons" and "oil control pots" throughout the city in 2008 and 2009, so that the vast number of Shanghai residents can truly experience the quantitative concept of "eating less salt and putting less oil" and turn the traditional propaganda slogan into a reality for residents.

Residents’ intake of cooking oil and salt decreased obviously, thanks to various health education and intervention led by the Shanghai municipal government in the past 10 years, which is a good aspect. On the other hand, we should also see that the intake of oil and salt for eating at home is still higher than the recommended standard. The recommended daily intake of oil and salt is no more than 25 grams per day, and the current intake of cooking oil and salt for residents is still far from the recommended level. Measures to control oil and salt should continue to be strengthened.

5. At present, it is common for residents to eat out (61% residents eat out). In addition to traditional intervention in family cooking, institutions such as restaurants and canteens should be intervened in the future.

From the monitoring data, we also found that the current rate of residents eating out is 61%, which is much higher than the national rate of urban residents eating out of 42%. The people who eat out in Shanghai are mainly young people aged 15-44. People used to eat at home, but now they eat out more and more. We can also see from ourselves that prepackaged foods (that is, packaged food, such as cakes, bread, sausages, etc.) has become a new choice. The development of science and technology has made life more convenient, and the rise of new consumption methods such as take-away and online shopping has affected the traditional family cooking habits. These changes pose new challenges to traditional nutrition intervention strategies.

The monitoring also found that the sodium intake of Shanghai residents was 4927.2mg, which was nearly 1.5 times higher than the recommended level. Excessive intake of sodium is closely related to the increase of blood pressure and the occurrence of hypertension. At present, the sodium intake of residents through salt accounts for 3/5 of the total sodium intake. Besides salt, sodium comes from salty condiments (such as soy sauce, monosodium glutamate, etc.), semi-finished dishes, pickled products, snacks, etc. (common sweet preserves also contain a lot of sodium), and vegetables also contain a certain amount of sodium. In the past, we actively advocated reducing salt intake, which can reduce sodium intake. As mentioned just now, residents’ eating style has changed. More and more people eat out, and they choose more packaged foods. In order to control the intake of sodium, besides controlling the intake of salt, they also reasonably choose condiments, packaged foods and snacks containing sodium.

In the past, our intervention measures to control oil and salt covering the whole city have made great achievements, but the intake of oil and salt for residents to eat at home is still higher than the recommended level. For future intervention and publicity, we will continue to strengthen the implementation of intervention measures to control oil and salt. On the other hand, we will also keep pace with the times, not only to continue to publicize the knowledge of reasonable nutrition for residents, but also with the popularity of residents eating out. Centralized dining halls, restaurants, take-away service providers, and prepackaged foods enterprises will also be the key targets for nutrition promotion in the future, advocating the supply of catering and food with "reducing salt, limiting oil and reducing blood sugar", encouraging dining places to carry out nutrition propaganda, formulating easy-to-understand nutrition labels in prepackaged foods, and guiding residents to choose food reasonably.

In addition, it is recommended that everyone eat at home, adhere to the habit of cooking at home with less oil and salt, and at the same time, eating at home also promotes the emotional exchange and promotion of family members.

6. Insufficient calcium intake is common, and residents drink less milk every day. It is suggested that residents increase the frequency of drinking milk and increase the intake of soybeans and bean products.

Our traditional Chinese diet is mainly based on plant food, which is conducive to the prevention of chronic diseases, but it also has an obvious defect, lacking a good source of calcium. Milk is a good source of calcium, and Chinese diet does not contain milk. A good phenomenon found in this monitoring is that residents have the habit of drinking milk, 41.6% residents consume milk every day, and 71.4% students consume milk every day. However, 86.8% residents still have insufficient calcium intake. Milk supplements the calcium that is insufficient in daily diet. Calcium is an integral part of bones and teeth, and it is an important nutrient for physical growth and bone development. Calcium deficiency will affect normal growth and development and cause osteoporosis. The Dietary Guidelines for China Residents (2016 Edition) recommends that each person should take 800mg of calcium daily, and students in the growth stage need 1000-1200mg. Every 100ml of milk contains about 104mg of calcium. In addition to the calcium in daily diet, 300ml of milk is needed every day. At present, the monitoring results show that the daily milk intake is insufficient. The average daily milk intake of residents is 97ml, and that of primary and secondary school students is 150ml.

Encourage residents to increase the amount of milk they drink. If the single intake is small, they can increase the number of times they drink milk, improve the calcium intake level and ensure the normal demand of the body. People who are lactose intolerant can choose low lactose milk or yogurt. At the same time, soybeans or bean products are also a good source of calcium. The Dietary Guide for Residents in China recommends that they consume 25g soybeans or a considerable amount of bean products every day. At present, residents’ intake of soybeans and bean products is less than half of the recommended amount. It is suggested that residents increase their intake of soybeans or bean products.