How did it become a "stem" for the whole network to flood with X-famous sentences posted by my brother?

       Only by reading this sentence, other friends must be very clear — — I’ve lost everything in this battle of pretending to be X. And this brother who posted it was nicknamed "Red Wall Brother" and "Terran Emperor" by others.

       In order to cooperate with the ridicule of other bar friends, Brother Red Wall himself has posted many times. It seems that he is "one-sided" but actually ridicules his response, which is a good show for many musicians.

Ranger 7

       It is also the incomparable classic reply of Brother Red Wall, which gradually spread from the post bar and even spread to every corner of the Internet. Even when I was watching League of Legends World Series, I couldn’t escape the attack of the red wall sentence.

       Just when RNG was at T13: 0, a few bullets floated past, which made me feel a little sad at once.

Ranger. com 8

       It seems that in just one night, this reply has become the famous stem of a hot Internet — — But even if a stalk is interesting, it will naturally rot if you talk too much.

       Soon, some people said that they felt uncomfortable at the sight of this sentence, and there was quite a case of "Juezi allergy" recurring. Brother Red Wall himself even replied, saying that he really didn’t expect such a ridicule to become like this, but now his brother’s post account seems to have been cancelled — — The appearance of "Brother Red Wall" was quite abrupt, which made people somewhat caught off guard, and this departure was even more surprising.

Ranger.com 9

       However, it is also the time when the classic reply of Brother Red Wall triggered the imitation of the whole network. This post about the competitive power of giant red fish seems to have been completely ruined. The following is full of imitators of Brother Red Wall and similar sentences.

       But some people have new inspiration after this. Since "Wang Feng is here" can have a typical example like Brother Red Wall, why can’t other brothers who post it show their strength under this power post?

       For example, just let the elder brother of the fishing bar wave the fishing rod a few times. According to the theorem of "the fisherman will always be in the air force" and "the fisherman will do everything except fishing", this red fish quickly evacuated in order not to be transferred.

Ranger. com 10

       What’s more, I think that only some brothers need to show their XP system, so that the fish can turn around and escape.

Ranger. com 11

       Although Brother Red Wall’s reply has been widely circulated in just a few days, it has great potential to become the next "rotten stalk of the whole network", but some friends’ speeches are quite pertinent.

       After all, nowadays, when we talk about post bars, we will think of many sentence patterns full of rage and aggression. This sentence from Brother Red Wall is not only quite mild, but also just a joke with no practical significance.

Ranger. com 12

       Of course, this red fish post can get widespread attention in "Wang Feng is in the bar", and even set off a discussion upsurge of the whole post bar, mainly because of the traditional culture of this post bar.

       Just listen to the name, I think many people will pop up many question marks: Wang Feng? Is Wang Feng here? This is a fan of singer Wang Feng, right? Why do you discuss these strange contents?

Ranger. com 13

       But in fact, this post has nothing to do with Wang Feng himself. The reason why it has such a name is only because the original bar owners ID was "Wang Feng is here". The traditional culture of the whole post bar is: cross-border combat power competition regardless of region.

       For example, this ladder map of combat power, which is the most widely circulated in Wangba, can fully reflect the hobbies of these old friends, although it has different expressions with the "version update" and the selfishness of some bar friends.

Ranger network 14

How to troubleshoot RAID 5 in the server

How to troubleshoot RAID 5 in the server

  Due to the continuous progress of technology, different types of servers have different treatment methods after RAID 5 failure.

  At present, the network topology structure of large-scale application programs generally adopts C/S structure or B/S structure, and at least one server with a large database needs to be placed in the central computer room. Considering the security and reliability of the server, RAID (Redundant Array of Inexpensive Disks) is usually used for redundant backup of the server’s disks. Among them, RAID 5 array level is parity disk array without independent parity disk, which adopts data blocking and independent access technology, can process multiple access requests in parallel on the same disk, and allows any hard disk in the array to fail.

  In practical application, due to some inevitable objective reasons, some array failures may occur. The most common situation is that the hard disk automatically goes offline, and the online status is displayed as DDD (invalid disk drive), and the hard disk has physical or logical failure. If it is a physical fault, only the hard disk can be replaced; If it is a logical fault, it can be repaired by targeted technology to restore the online state of the hard disk, continue to maintain the striped distribution of the hard disk data in its original array, and continue the consistency of the data storage system.

  However, the data recovery of some old HP servers (such as HP LH6000) is different from that of new HP servers (such as HP ProLian series servers). Therefore, different servers handle RAID 5 failures differently. I have been in contact with the data failure of RAID 5 array card caused by unexpected power failure of two servers, and solved the problem by adopting different strategies.

How to troubleshoot RAID 5 in the server 1

Fault repair

  One is HP LH6000 server, and four 18GB hard disks are made into RAID 5 disk array, and its array card is NetRaid. The other is HP ProLian ML370 server. Four 146GB hard disks are made into RAID 5 disk array, and its array card is Smart Array 642 with Hot Spare hard disk. Both operating systems are Window 2000 and the database is Server 2000.

  The fault of HP LH6000 is as follows: one hard disk is flashing red light, and the machine is still running normally, but it will not be long before the system can not run normally, and then it is found that the red light of another hard disk is flashing.

How to troubleshoot RAID 5 in the server 2

The solution is as follows:

  1. start the server, and press Ctrl+M to enter the NetRaid management program when self-checking to the array. Check the array information and find that the hard disk status is Failed, and use the modified configuration to forcibly set a hard disk to OnLine. Restart the server, the hardware self-check before entering the system is invalid, and the startup fails.

  2. Start the server, and press Ctrl+M to enter the NetRaid management program when self-checking to the array. Select the disk array, manually Fail the hard disk that was originally hung OnLine, and then manually set another Failed hard disk to OnLine, and restart the server to enter the system.

  3. After checking that the system and database are running normally, enter the array configuration tool and manually set the Failed hard disk to Rebuild, and then restart the server after 100% reconstruction. All arrays and systems are restored to their original state.

  Another server running ERP system (HP ProLiant ML370) is configured as a RAID 5-level disk array by four 146GB hot-swappable hard disks through RAID cards (Smart array array cards). One of the hard disks suddenly broke down during operation. Server RAID 5 automatically enables the Hot Spare hard disk to logically replace the damaged hard disk. The data access task of the whole hard disk still runs completely in the original reading and writing process sequence, and the application program and database have no influence.

  Check the hard disk status through the ACU tool that comes with HP, and find that the hard disk with red light warning is offline. If there are two red lights on Raid 5 in HP ProLiant server, it indicates that the system has crashed and the database cannot be accessed, but the system will not shut down automatically. When the second hard disk is red, the data can’t be recovered by conventional means, so we have to pay a professional third-party data recovery company to recover the data.

How to troubleshoot RAID 5 in the server 3

  Therefore, for the old HP LH6000 series servers, the array design is quite different from that of the current HP ProLiant series servers. As far as the operation method is concerned, there are many options for the array operation method of HP LH6000 server, including deleting the array again and rebuilding it after the array fails, and the initialization is also manually selected. However, the initialization of HP ProLiant series server array is automatically performed in the background after the array is configured, so the ProLiant series server cannot reconfigure the array after an array error.

  The HP LH6000 server will cause the disks in the array to be disconnected for other unexpected reasons, so the maintenance personnel can manually choose Online or Offline, Rebuild, etc. to restore the data. However, the current HP ProLiant series servers will no longer have the phenomenon of disk disconnection in the array like the old servers, so when the hard disk is red, it is basically damaged and needs to be replaced. Of course, you can choose to Rebuild the hot-plug hard disk and see if the hard disk can be used for a while.

How to troubleshoot RAID 5 in the server 4

Do a good job of technical backup

  From the above two examples, it can be seen that the troubleshooting of Raid 5 disks of servers of the same brand and different series is different because of their different embedded technologies. But after Rebuild the data, the data was saved, from which the following experiences can be drawn:

  We believe that any advanced technical means is not foolproof. If you want to ensure data security, you must do a good job of backup, and it is best to do a remote backup of the database once a day. Spare at least one new hard disk. It should be pointed out that the hard disk that joins the array must be greater than or equal to the capacity of the failed hard disk.

How to troubleshoot RAID 5 in the server

  If conditions permit, the array creation scheme of "RAID 5+ hot spare" is recommended. This way, we have two chances to replace the hard disk before the data is lost. For general applications, only RAID 5 is needed, which can provide data access performance, reliability and maximum disk space at the same time.

  Administrators must always observe the status of the array, including the yellow warning light of the disk array and the drive status in the management software. Trouble shooting in time. No matter what level of array, data backup should be done before troubleshooting.

Have you found the answers to all the n kinds of legends about Sanxingdui?

  Xinhua News Agency, Chengdu, March 20th Question: Have you found the answers to all the N kinds of legends about Sanxingdui?

  Xinhua News Agency reporters Wang Peng, Shi Yuxi and Tong Fang.

  With the announcement of new archaeological discoveries in Sanxingdui site, people’s eyes once again focus on this magical land.

  Since the discovery of No.1 and No.2 "sacrificial pits" in Sanxingdui site in 1986, people have never stopped discussing it. A large number of shocking and mysterious cultural relics unearthed in the "sacrificial pit" have aroused a lot of speculation in the world.

  Have you found the answers to those legends about Sanxingdui?

  Legend 1: Is Sanxingdui an alien civilization?

  Sanxingdui bronze vertical mask (Xinhua News Agency)

  Huge ears, bulging eyes, and a big mouth wide to the ears … … Some people who eat melons believe that Sanxingdui is an alien civilization, and the grotesque bronze masks, bronze statues, bronze sacred trees and other cultural relics of Sanxingdui are alien works.

  Experts are firmly opposed to this statement! The ancient Shu civilization, represented by Sanxingdui, is an important part of the pluralistic origin of Chinese civilization. Among the cultural relics unearthed in Sanxingdui, bronze statues, bronze rings, jade Zhang, jade cong, jade bi and jade ge are consistent with the Yellow River basin, which shows that Sanxingdui has the common attributes of Chinese culture. The familiar cultural relics with strange shapes and magnificent atmosphere, such as bronze standing man, bronze sacred tree and bronze vertical mask, not only show the brilliance of ancient Shu civilization, but also show the richness and diversity of Chinese culture.

  In other words, Sanxingdui civilization is "made in China" and has nothing to do with aliens.

  Legend 2: Sanxingdui people "moved" to Jinsha?

  The gold mask unearthed from Jinsha site (left) and the newly discovered gold mask in Sanxingdui (imposition picture)

  The newly discovered gold mask of Sanxingdui "made a stunning appearance", and the sharp-eyed netizens saw at a glance: this is the same as the gold mask of Jinsha! Not only the gold mask, but also the ornamentation, jade Zhang, jade chisel, ivory &hellip on the golden crown belt of Jinsha and the golden staff of Sanxingdui; … There are many cultural relics in the two sites. So can we think that people from Sanxingdui "moved" to Jinsha?

  Experts believe that this high similarity between Jinsha site and Sanxingdui site proves that they belong to the same cultural system, and there must be some special connection between the two sites. Combined with the archaeological findings in recent years, we can think that Jinsha culture is the inheritance and development of Sanxingdui culture, and both of them have become an important part of the development of ancient Shu civilization.

  Legend 3: Sanxingdui Archaeological Excavated "Angry Birds" with the same pig?

  "Angry Birds" with the same pig (Xinhua News Agency)

  Just last July, Sichuan Institute of Cultural Relics and Archaeology announced that an important site — — Joint site, unearthed a large number of cultural relics. Among them, a clay pottery pig is cute and cute, which is very similar to the villain green pig in Angry Birds. Netizens exclaimed: Is this the predecessor of Angry Birds?

  In fact, experts believe that the joint site of this clay sculpture pottery pig unearthed should be an important settlement around the ruins of Sanxingdui ancient city. The joint site covers four cultural factors, namely, Guiyuan Bridge, Baodun Bridge, Sanxingdui Bridge and Twelve Bridges. It is the first time that a complete sequence of ancient Shu civilization has been found around Sanxingdui. Among them, the main cultural factors of Sanxingdui are the most abundant in the joint site, and a large number of cultural relics similar to Sanxingdui have been unearthed.

  There are not only "villain green pigs", but also a large number of high-handled beans, hollowed-out beans (plates) and small flat-bottomed cans have been unearthed and restored at the joint site. It is worth mentioning that the pottery with the combination pattern of dragons and phoenixes carved on the yinxian line was unearthed in the late Shang Dynasty, and it is the earliest pottery with the pattern of "dragons and phoenixes are auspicious" found in China.

  Legend 4: The "bronze giant" holds a "selfie stick" in his hand?

  Sanxingdui "Bronze Man" (Xinhua News Agency)

  Among the numerous bronze statues in Sanxingdui, the "bronze giant" is well known. Its overall image is solemn and solemn, and its hands are hollow. For a long time, people have been speculating whether he holds some kind of instrument in his hand. Even naughty netizens think that he is holding a "selfie stick" in his hand.

  At present, there is no final conclusion on this issue in academic circles. Experts discussed that the "bronze standing man" may hold ivory, jade cong or scepter. The "Bronze Big Liren" wears a high crown, narrow sleeves and a half-arm-style three-layer dress, with complex and exquisite clothes, mainly dragon patterns, supplemented by bird patterns, insect patterns and eye patterns, and plaid stripes. It seems that his identity is an ancient Shu "high priest" with extraordinary skills.

  There is no end to the exploration of Sanxingdui civilization.

  Up to now, archaeologists have unearthed more than 500 important cultural relics in the six Sanxingdui cultural "sacrificial pits" newly discovered at Sanxingdui site.

  I believe that in the future, through the detection and analysis of these cultural relics, more puzzles about Sanxingdui will be revealed. The true face of this ancient civilization, which has been buried deep underground for 3 thousand years, will become more and more clear.

  We will wait and see … …

Gold or gold? The gold price must prove that "the annual increase of 1.7% still exists" and the long-term fundamental supply and demand are challenged.

  Whether the safe-haven value of gold still exists or not has become a hot topic of concern to many market investors. From a fundamental point of view, the price of gold must prove that the annual increase of 1.7% still exists, but the long-term fundamental supply and demand are being questioned and challenged.

  Chimp Investor columnist Peter Elston mentioned that he considered what he could learn from the long-term price trend of gold, the so-called technicality. The final conclusion is that although the inflation-adjusted return of gold may still be poor in absolute value in the short term, it may still be better than that of stocks, bonds and cash, especially if the inflation rate remains high in the next few years.

  He also suggested that in the past 50 years, the inflation-adjusted annual appreciation trend of gold price should remain unchanged at 1.7%, because the growth rate of global real wealth may continue to exceed this value. However, this is too simplistic and assumes that the fundamental reason for buying gold will not change much, which should be challenged.

  This article focuses on the root cause of gold’s popularity, its supply dynamics, and its fundamentals, to see if they still prove that the above historical trend, the actual price increase of 1.7% per year still exists.

  Gold is an iron-loving element, which means that it is heavy, easy to dissolve in iron, and doesn’t like to combine with oxygen. The oxide of gold is actually thermodynamically unstable. Therefore, its concentration is higher in the deep core and mantle than in the crust. Compared with the very low occurrence rate of the whole crust, the exploitable gold deposits are even rarer. In addition, the mineable deposits have now been exhausted, so that the annual output of gold has been flat since 2016. In the absence of major changes in mining technology and/or a drop in energy prices, this slowdown in annual output may continue.

  The chemical inertness of gold makes it very suitable for jewelry, electronic products, dentistry, aerospace and value storage as gold bars and coins. The World Gold Council estimates that by the end of 2021, 205,238 tons of gold have been discovered/mined in the past 6,000 years, and the proven unexploited reserves total 53,000 tons, the latter figure is lower than 54,000 tons in 2019. It is also estimated that there are 15,000 tons of gold dissolved in the world’s oceans, equivalent to about 10 parts per trillion.

  It is the inertia and rarity of gold that endows it with intrinsic value, that is, its practicality and practicality. Warren Buffett once wrote a famous saying that gold is dug out of the ground in Africa or somewhere, and then we melt it, dig a hole, bury it, and then pay people to stand around and guard it. It is not practical, and anyone who watches it from Mars will be puzzled.

  But Elston doubts that Buffett will shine in the short term, but he will surely see that many people have done so for thousands of years and will almost certainly continue to do so. Besides, if he has a mobile phone or a tooth filling, he may benefit from the utility of gold to a greater extent than he is willing to mention.

  As for the use breakdown of 205,238 tons of above-ground inventory, jewelry accounts for 46%, privately owned gold bars, coins and ETFs account for 22%, the central bank accounts for 17%, and other uses such as electronics, dentistry and aerospace account for 15%. It is estimated that as much as 80% of the newly mined or recycled gold is used for jewelry manufacturing.

  Looking forward to the future of gold, it needs to be clear that Elston is not interested in the factors that may affect the short-term price performance of gold. They are essentially emotional-driven and unpredictable. In addition, compared with the long-term possible percentage change, the short-term performance is insignificant.

  In other words, the really important factors are those related to basic supply and demand. They will determine the long-term performance of inflation-adjusted gold prices. For example, whether it will increase by 300% or decrease by 75% in the next decade. In his view, this is exactly what the market should pay attention to, not whether the nominal price of the US dollar will fall below $1,500 in the next few weeks.

  As mentioned above, the annual gold production has been declining and has been flat since 2016. Environmental problems limit the potential of new discoveries. The progress of mining technology is related to the use of unmanned aerial vehicles, virtual reality, self-driving cars and blasting optimization. They didn’t, in fact, solve the basic law in a meaningful way, that is, the deeper you want to dig, the more energy you need.

  Although 75% of the annual gold demand is met by mining gold supply, the shortage is made up by recycling, mainly jewelry. In the short term, the supply of recycled gold is sensitive to the price of gold. In addition, the dynamics behind the basic supply of recycled gold are unlikely to change significantly.

  About 6000 years ago, the first known use of gold was as decorative beads. It is hard to see how this established popularity will fundamentally change. According to the data of the World Bank, since 1971, the real GDP of the world has increased by 3.1% every year, while the appreciation trend of the real gold price in the same period is 1.7% every year. Generally speaking, in the past 50 years, the world’s real GDP has increased by 360%, which is 130% higher than the real gold price. In other words, the rise of gold prices in the past 50 years has been supported, proved and explained by the growth of global wealth.

  In recent years, the net purchase of gold by central banks has been quite stable, with an average of about 500 tons per year. The use of gold, whether as jewelry or as a means of value storage, is inseparable from its chemical characteristics. Therefore, it seems unlikely that central banks will lose interest in holding physical gold in their vaults in the near future or even the distant future. Net purchases may vary from quarter to quarter, sometimes very different, but the long-term trend seems to have been established.

  The demand for private investment in gold is probably the most interesting of the four main sources. Its utility as a private value store is similar to that of the central bank, that is, it is related to its chemical properties. However, economies of scale make it expensive and/or risky for private individuals to store gold at home, so most people hold gold in paper form, that is, certificates and ETFs. Proponents of cryptocurrency have seized this obvious inefficiency, claiming that things like bitcoin should be regarded as digital gold, thus invalidating the current utility of gold as a private sector value store.

  The use of gold as jewelry and storage of private and public values is inseparable from its chemical characteristics, in other words, the demand for gold bars goes hand in hand with the demand for jewelry. Bitcoin and other cryptocurrencies don’t have such basic attributes, and they never will. A USB flash drive storing encrypted access codes is unlikely to be worn as jewelry. Unless, of course, they are made of gold.

  Elston said that the most interesting reason for the demand for private investment is that in difficult economic times, gold may be sold to buy more necessities, thus putting downward pressure on prices. However, in the severe economic difficulties, due to high inflation, people lose confidence in legal paper money, and the demand for it as a means of value storage will increase.

  He is not sure whether he wants to live in a world where gold has replaced paper money as the main currency, but this does not mean that economic difficulties will continue but increase gradually in the long run. For example, global temperature rise, war, famine and epidemic diseases will not lead to the appreciation of gold prices.

  Describe the various ways of gold, namely, value storage, inflation hedging, safe haven and investment. As should be clear, value storage is something that actually keeps its value. Gold has always been a means of value storage, and its inflation-adjusted price has shown an upward trend in the past 50 years. However, if you bought gold in 1981, you are actually still underwater. In other words, the actual decline of gold may exist and has existed for a specific period of several decades.

  The reputation of gold as an inflation hedge tool was established in 1970s, 1980s and 1990s, but the relationship has not been obvious since then. It is true that in naughty times, when inflation fell, the real price of gold rose by more than 400%. Therefore, Elston is not sure whether the argument that gold is an inflation hedging tool is valid, except in severe economic difficulties, such as the use of hyperinflation in Germany.

  Is gold a safe haven, that is, defensive? In other words, when risky assets such as stocks and high-yield bonds perform poorly, does it perform well? Similarly, there is no real evidence that this is indeed the case. It has not performed well this year, which is a period of poor performance of risky assets.

  Finally, Elston never considered physical gold as an investment. This is because physical gold is different from stocks, bonds or property, and the former does not actually generate income. It is more similar to cash, and the portfolio allocation of physical gold should be regarded as a cash substitute. He finally stressed that this does not mean that high cash distribution is appropriate, and gold should be more popular as cash than legal tender.

From human pox to vaccinia, human beings open the "box" of vaccines.

  Throughout modern history, smallpox has held the top spot in killing human beings.

  Smallpox is also the first infectious disease eliminated by human beings.

  When future generations are exploring what killed smallpox, the trekking about how human beings overcome diseases step by step has merged into the long river of human medical history.

  It is necessary for us to wade into this river at any time, go back to the way we came and find hope for the future.

  The pockmarked emperor and the milkmaid

  It is mentioned in Huangdi Neijing that "poison" should be used to treat diseases, and the so-called "fight poison with poison". Traditional Chinese medicine began to use this method to deal with smallpox, which existed during the Tang and Song Dynasties. Doctors take out the serous fluid from the abscess of smallpox patients and implant it into the body of healthy people for prevention and treatment, which is called human pox vaccination.

  During the Wanli and Apocalypse years of Ming Dynasty, various books about human pox appeared. By the Qing dynasty, the method of preventing smallpox by human pox vaccination was widely promoted. Kangxi, the "pockmarked-faced emperor" who had suffered from smallpox, set up a pox clinic under the Tai Hospital and recruited famous doctors. Also in Beijing, a special "acne check chapter Beijing" is set up to take charge of the Eight Banners’ acne prevention. He specially sent people to welcome Ayla Zhang, a well-known folk vaccinia doctor, into the palace to vaccinate the royal family and banners.

  Jared diamond, an evolutionary biologist and anthropologist, once revealed how the human body can defeat the virus: in the process of resisting a certain pathogen that infects the human body, the human body will gradually form specific antibodies, which makes it unlikely to be infected by the same pathogen again after recovery.

  In the thousands of years of confrontation between human beings and smallpox, the latter has occupied an absolute advantage for a long time, and "pockmarked face" is so common that people without pockmarked face become special.

  The 18th century was the age when smallpox ravaged Europe, and the British doctor edward Cenna (1749-1829) devoted himself to studying the solution. He noticed that almost all the female milkmaids had no "pockmarked faces". The beautiful milkmaid aroused Qinna’s curiosity, and he found one thing in common with them — — Cowpox of a milkmaid.

  Vaccinia is a virus that can be co-infected by humans and animals, but it does no serious harm to cattle and people. There is a saying in the English countryside that "as long as you have suffered from vaccinia, you will not get smallpox".

  Since 1788, Qinna began to carry out experiments on animals, using vaccinia of dairy women instead of smallpox patients to fight smallpox. For 8 years in a row, the experiment pointed to the same result, and vaccinia can effectively prevent smallpox.

  On May 14th, 1796, Qinna conducted the first human experiment. He took the serous fluid Sarah Nelmes, a milkmaid, and inoculated it on the arm of phipps, an 8-year-old boy. Two months later, he inoculated phipps with real smallpox slurry. As a result, the boy was not infected with smallpox, and the previous vaccination seemed to have made him immune.

  In the following two years, Qinna conducted the same human experiment many times, and the results were the same: all children who had had vaccinia were immune to smallpox virus. In 1798, Chennault announced that smallpox could be prevented by vaccination.

  Vaccinium vaccination spread rapidly around the world. In 1977, Ethiopia recorded the last case of smallpox in human history. On October 26, 1979, WHO officially publicized that smallpox was eradicated all over the world.

  This is the first time in human history to win the battle against infectious diseases.

  Fatal bacteria and life-saving bacteria

  Although the practical application of vaccinia technology is very successful, scientists are not satisfied. People need to explain theoretically why vaccinia can fight smallpox.

  In the 1950s, chemist Louis Pasteur confirmed the relationship between diseases and germs, and found that specific microbial pathogens could cause specific diseases. Moreover, he found that the long-term growth toxicity of bacteria on artificial culture medium would be weakened, but the immunogenicity still existed.

  According to this theory, in 1881, Pasteur artificially attenuated Bacillus anthracis with strong immunogenicity and inoculated it into sheep, which finally proved that sheep inoculated with Bacillus anthracis vaccine would not get the disease again.

  Rabies virus can not be isolated and cultured like bacteria, but Pasteur confirmed that the pathogenic microorganism causing rabies exists in the spinal cord or brain tissue of sick animals. Therefore, he chose rabbit brain for subculture to obtain attenuated strains, and then successfully made live vaccines.

  With the development of microbiology and immunology, vaccine is really defined as active immunity preparation for preventing infectious diseases, which is made of pathogenic microorganisms (such as bacteria, rickettsia, viruses, etc.) and their metabolites by artificial attenuation, inactivation or genetic engineering.

  Based on this method, more vaccines can appear. Attenuated live vaccine made by heating inactivation of Vibrio cholerae; After 13 years and 213 generations of continuous culture on the culture medium, attenuated BCG was obtained.

  With the development of the discipline, some traditional classical vaccine varieties have been further transformed into new vaccines, and some vaccines that cannot be developed with classical technology have found ways to solve the problem.

  In 1972, recombinant genetic engineering contributed a lot of technical support and gave birth to recombinant gene vaccine. By using DNA recombinant biotechnology, natural or synthetic genetic material which can induce immune response in protein of pathogen shell can be directionally inserted into bacteria, yeast or mammalian cells, and the vaccine can be made after expression and purification. Nowadays, BCG, recombination vaccines, SARS vaccine, HIV vaccine and highly pathogenic avian influenza vaccine are being studied.

  Conjugate vaccine appeared in 1980s. Scientists linked sugar molecules with protein (toxoid of Clostridium tetanus or diphtheria) by chemical methods, and developed a conjugate vaccine. Vaccines against pneumonia and meningitis are made in this way.

  Looking at the present, the vaccine that has attracted much attention is none other than nucleic acid vaccine. Nucleic acid vaccine, also known as gene vaccine or DNA vaccine, transports DNA vaccine to human cells through some carrier (such as nanoparticles), which will guide the cells to produce immune active components, and then the cells will "spit out" these active components to stimulate the human body to obtain corresponding immunity, but it will not cause disease.

  Nucleic acid vaccine can even transfect food cells, such as inserting hepatitis B virus nucleic acid vaccine into the genome of tomato cells, and inoculating the vaccine when eating tomatoes.

  Scientific and technological progress brings infinite possibilities, and the new exploration of vaccination methods is also the tireless pursuit of scientists. In addition to traditional injection methods, oral administration, skin patch, nasal spray and improved fruit are all targets.

  A never-ending struggle

  With the development of immunology research, people have more and more expectations for vaccines, hoping that they will not only "prevent diseases". Researchers are already in action, trying to achieve the effect of treating diseases or preventing diseases from worsening by inducing specific immune responses. Such vaccine products are therapeutic vaccines.

  There are many therapeutic vaccines that have been studied all over the world: tumor vaccines used for tumor treatment use tumor antigens for active immunization to stimulate the body’s active specific immune response to tumors to prevent the growth, spread and metastasis of tumors; Vaccines used for the treatment of cardiovascular diseases aim at intervening the immune process to prevent the occurrence and development of atherosclerosis (AS). A Swiss biotechnology company said that CYT006-AngQb, a vaccine used to treat hypertension, has a good clinical development prospect … …

  On the other hand, when human beings are struggling to move forward, the "perpetrators" of infectious diseases are not willing to be silent. Since 1970s, more than 40 infectious diseases have been discovered in the world, such as HIV virus, avian influenza virus, SARS virus, mad cow disease prion, monkeypox virus, Lyme virus, Ebola virus, Legionella, Vibrio cholerae O139 and so on. People’s common influenza viruses are constantly innovating. For example, after the "Spanish flu" caused by H1N1 virus, the "Asian flu" and the "Hong Kong flu" were staged by H3N2 subtype virus. Or a lower-grade flu, it is staged almost every few years in Europe, America and Asia. There are also new viruses that have never met each other, eyeing and hiding in the dark.

  "The only competitor competing with humans for the dominance of the earth is the virus." The words of lederberg, the winner of the Nobel Prize in Physiology or Medicine in 1958, sounded like an alarm bell. In the past two hundred years, the confrontation between human beings and germs was the fiercest. For the first time, we turned the tables, stood in a pre-emptive position, and seized the throat of the biggest killer of human beings. Compared with the end of the 19th century, the average life expectancy of human beings has been extended for several decades.

  We have opened the "box" of vaccines. Overcoming the challenge of disease again and again makes us believe that disease creates problems and also provides understanding.

  Huaxi Dushi Bao-cover journalist Li Yuanli

  [References]

  1. zhangfang, from human pox to cowpox [J], Science World, 06, 2018;

  2. [America] jared diamond, Guns, Germs and Steel, Shanghai Translation Publishing House;

  3. Huang Jiandong, the milestone of human conquest of smallpox — — Jenner’s Invention of Vaccinium Inoculation [J], Invention and Innovation, 2003, (9): 42-43;

  4, Liu Xueli, China’s ancient immune thought and human pox vaccination [J], Medicine and Philosophy, 1993 (11);

  5. Kou Yi, Brief Introduction of Three Vaccine Revolutions [J], Chinese Journal of Medical History;

  6. Plotkin, Vaccine Science (5th Edition) (Fine), People’s Health Publishing House, 2011;

  7. Xie Zhongping and Li Qihan, Fighting Infectious Diseases: Application and Development of Vaccines, 2007.

Fight the tough battle of agricultural non-point source pollution prevention and promote the sustainable development of agriculture

  At present, China’s agricultural and rural economic development has entered the best historical period, and grain production has achieved "11 consecutive increases", which has been stable at more than 1.2 trillion Jin for two consecutive years. At the same time, it has made great achievements and paid a huge price. The string of resource utilization is getting tighter and tighter, and the carrying capacity of the ecological environment is getting closer and closer to the limit. Facing the double "curse" of resource conditions and ecological environment, it is urgent to change the mode of agricultural development, strengthen the control of agricultural non-point source pollution, effectively promote the protection and control of agricultural ecological environment and promote the sustainable development of agriculture.

  First, scientific graspAgricultural non-point source pollution situation, and effectively enhance the sense of urgency and responsibility of agricultural non-point source pollution prevention and control work.

  The first national pollution survey showed that in 2007, the chemical oxygen demand (COD), total nitrogen and total phosphorus emissions from agricultural sources in China reached 13.2 million tons, 2.7 million tons and 280,000 tons respectively, accounting for 43.7%, 57.2% and 67.4% of the total national emissions respectively. Among them, livestock and poultry breeding sources account for 96% of agricultural source COD, and are the main "contributors" of agricultural non-point source pollution. Agricultural chemicals such as livestock and poultry, aquaculture, chemical fertilizers, pesticides and agricultural films are the main sources of pollution. Different from industrial point source pollution directly entering the water body through centralized sewage outlets, agricultural non-point source is decentralized, and its pollution process is not a simple direct causal relationship from agricultural production behavior to discharge, and finally to environmental impact. The research shows that 35% of nitrogen in farmland chemical fertilizer in China is utilized by crops in the current season, and most of the rest is retained in farmland soil, and a small amount flows into ditches, and finally less than 5% enters the surface water body through runoff. Therefore, although the total amount of agricultural source pollutants discharged in China is relatively high, the amount that actually enters the water body is still very limited.

  At present, the situation of agricultural non-point source pollution is generally grim, but there are also some particularities, which require us to make careful judgments and make precise policies.

  First, the intensive degree of aquaculture is getting higher and higher. Due to the low resource utilization rate of livestock manure and other wastes, pollution emissions are on the rise.In recent years, the total amount of livestock and poultry breeding in China has been increasing. In 2013, the number of live pigs slaughtered in China exceeded 700 million. At the same time, the scale and intensification have developed rapidly, and the proportion of large-scale breeding of more than 500 pigs per year has reached 40.8%. At the same time, the construction of livestock waste treatment facilities is relatively backward, and a large amount of livestock manure is difficult to be treated and utilized in time, which makes livestock waste change from traditional farmyard manure to pollutants. In addition, the scale of aquaculture in China is also expanding rapidly. In 1978, the total amount of aquatic products was 4.654 million tons, of which artificial aquaculture accounted for 26.1%. In 2013, the total amount of aquatic products reached 61.72 million tons, accounting for 73.6%. A large number of bait and fish medicine were put into aquaculture, which caused water pollution.

  Second, the amount of chemical fertilizer used in the main grain crops is basically reasonable, and the phenomenon of excessive application of economic crops such as vegetables and melons is more prominent. On the whole, the growth rate of chemical fertilizer consumption is declining, but the amount of chemical fertilizer input is still too large.In 2013, the amount of chemical fertilizer used in China was 59.12 million tons, accounting for 35% of the world. Based on 2.03 billion mu of cultivated land, the average amount of chemical fertilizer used per unit area reached 436.8 kg/ha, which was far higher than the world average. It is worth pointing out that at present, the average amount of nitrogen fertilizer used in China’s main grain crops is about 212 kg/ha, which is lower than the upper limit of environmental safety (the upper limit of safety set by developed countries for preventing water pollution is 225 kg/ha), but the average amount of nitrogen fertilizer used in fruit trees and vegetables is far higher than the environmental safety requirements, and the phenomenon of excessive application of chemical fertilizers in orchards and protected vegetables is still prominent.

  Third, the use of pesticides per unit area is higher than the world average, but lower than that of developed countries such as the United States. The overall usage tends to be stable, but the utilization rate is low.In recent years, the amount of pesticides used in China has stabilized at about 320,000 tons (active ingredients), accounting for 1/7 of the total amount of pesticides used in the world, which is higher than the proportion of China’s land area to the world’s cultivated land area, which is related to the high land multiple cropping index in China. Generally speaking, China’s pesticide consumption per unit area is higher than the world average, but lower than that of developed countries such as the United States, Israel and Japan. On the other hand, at present, the utilization rate of pesticides in China is low, only 35%. Residual pesticides enter water bodies through precipitation, surface runoff and soil infiltration, which will lead to the deterioration of soil and water environment quality, destroy ecology and affect biodiversity.

  Fourth, the recovery rate of plastic film is low, and the problem of residual old agricultural film still needs to be solved.China’s total use of plastic film and crop coverage area rank first in the world. In 2013, the consumption of agricultural film in China was 2.493 million tons. Due to the extensive use of ultra-thin plastic film and the lack of recycling technology and mechanism of residual film, the "white revolution" gradually evolved into "white pollution", and the problem of residual pollution of farmland plastic film became increasingly prominent. Plastic film residue is serious, affecting soil structure and reducing cultivated land quality; Affect the emergence of seedlings, resulting in reduced production; Affect the operation of agricultural machinery, resulting in a decline in the quality of sowing and fertilization; Livestock eating by mistake occurs constantly, which is harmful to livestock health.

  Fifth, the comprehensive utilization rate of crop straw is low, and the recycling capacity needs to be improved urgently.Crop straw is a versatile agricultural resource. It is estimated that in 2013, the total output and collectable amount of straw in China were 964 million tons and 819 million tons, respectively. The actual utilization amount was about 622 million tons, and the comprehensive utilization rate was only 76%. With the change of agricultural energy structure, the proportion of crop straw in domestic energy is less and less. The way out for excess straw is: firstly, burning on the spot will cause air pollution, reduce atmospheric visibility, hinder traffic and endanger human health; Second, abandoned fields or piled into rivers or lakes, after weathering, rain and decay, the organic matter in straw enters the water body and causes pollution.

  Generally speaking, with the continuous improvement of agricultural intensification and the rapid development of aquaculture in China, the problem of agricultural non-point source pollution caused by excessive use of agricultural inputs such as chemical fertilizers and pesticides and unreasonable disposal of agricultural wastes such as livestock manure, crop straws and farmland plastic film residue has become increasingly prominent, which seriously restricts the sustainable development of agriculture and rural economy. Therefore, strengthening the control of agricultural non-point source pollution is a realistic need to ensure the safety of agricultural products, realize China’s food security and quality safety of agricultural products, and is an internal need to improve the agricultural ecological environment, accelerate the transformation of agricultural development mode and realize the sustainable development of agriculture. We must scientifically grasp the increasingly serious situation of agricultural non-point source pollution, deeply understand the great significance of strengthening the control of agricultural non-point source pollution, and earnestly enhance the sense of urgency and responsibility in our work.

  Two, the agricultural ecological environment protection and governance work has made positive progress, laying a solid foundation for the prevention and control of agricultural non-point source pollution.

  Agricultural non-point source pollution in China is a long-term accumulation, which has its particularity and complexity. It can’t be completely solved overnight, and it needs a long period of unremitting efforts. In recent years, while ensuring the development of agriculture, agricultural departments at all levels have continuously increased the protection and governance of agricultural ecological environment, initially established a team of agricultural non-point source pollution prevention and control and expert support teams, and gradually established and improved the policy system, exploring and forming a number of practical technologies and typical models, which have laid a good foundation for the fight against agricultural non-point source pollution.

  First, the construction of the system team has been continuously strengthened.A four-level agricultural environmental protection management system has been formed, with two state-level main stations as the leader, 33 agricultural environmental protection stations in provinces, autonomous regions, municipalities directly under the Central Government and cities under separate state planning as the main body, and 326 prefecture-level stations and 1794 county-level stations as the basis, which provides a team system guarantee for agricultural ecological environment monitoring and prevention and control.

  Second, the monitoring and early warning capabilities have been continuously improved.A national agricultural non-point source pollution monitoring network has been initially established, and the normal and institutionalized operation of agricultural non-point source pollution monitoring has been continuously promoted; A four-level cultivated land quality monitoring network at the national, provincial, municipal and county levels has been established, and an annual report on national cultivated land quality monitoring has been issued; An environmental monitoring network system covering China’s offshore bays, islands and reefs, beaches, nature reserves, aquatic germplasm conservation zone and aquaculture waters has been initially formed, and the Bulletin on Fishery Ecological Environment in China has been issued regularly. A national monitoring network for pollution of agricultural products was established to carry out heavy metal pollution investigation in the producing areas.

  Third, vigorously promote the scientific application of chemical fertilizers and pesticides.Comprehensively popularize the technology of soil testing and formula fertilization, with the promotion area reaching 1.4 billion mu; In-depth implementation of green prevention and control, the establishment of 150 national green prevention and control demonstration zones, the gradual elimination of 33 kinds of highly toxic pesticides, and vigorously promote the use of high-efficiency, low-toxicity, low-residue and biological pesticides; Carry out the integration of specialized unified prevention and control of crop pests and diseases with green prevention and control, promote pilot construction, and establish 218 demonstration bases; At the beginning of 2015, the Action Plan for Zero Growth of Fertilizer and Pesticide Use by 2020 was issued, and the zero growth of fertilizer and pesticide use was initiated.

  Fourth, actively promote pollution prevention and control of livestock and poultry breeding.Accelerate the standardization of livestock and poultry breeding, create 3,397 standardized demonstration sites, and effectively improve the level of pollution prevention and control of livestock and poultry breeding; Start the pilot project of comprehensive utilization of livestock and poultry waste; Develop rural biogas projects according to local conditions and improve the sewage treatment capacity of rural farming manure.

  The fifth is to carry out comprehensive utilization of straw in depth.Implement the comprehensive utilization project of straw, focusing on supporting Beijing-Tianjin-Hebei and other areas to carry out straw returning to the field, raising livestock, straw biogas, straw replacing wood, straw carbonization and other work; We will start the construction of a demonstration area for full quantitative utilization of straw at the township level in Beijing, Tianjin and Hebei, and accelerate the scale and industrialization of straw utilization.

  Sixth, efforts should be made to solve the pollution of farmland residual film.Revise the standard of plastic film to solve the problem that residual film is easy to break and difficult to recycle; For four consecutive years, the agricultural cleaner production demonstration project focusing on the recycling of waste plastic film was implemented, and the plastic film recycling and processing system was initially established; Arrange subsidies for dry farming technology such as plastic film mulching in northwest and north China to promote the popularization and application of high-standard plastic film; The comparative test of degradable plastic film was started, and the degradable plastic film with good application effect was screened for demonstration and popularization.

  Seventh, work together to promote the demonstration construction of comprehensive management of agricultural environment.A typical driving system of modern eco-circular agriculture has been formed, which consists of 1 eco-circular agricultural pilot province, 10 circular agricultural demonstration cities, 283 national modern agricultural demonstration zones, 1,100 beautiful countryside and several eco-agricultural demonstration bases. In key river basins and important water source protection areas, we will implement the construction of demonstration zones for the comprehensive prevention and control of livestock and poultry breeding wastes and agricultural nitrogen and phosphorus pollution, and actively explore effective mechanisms for the prevention and control of agricultural non-point source pollution in river basins.

  To sum up, in recent years, the positive results of agricultural ecological environment protection and governance, as well as the continuous improvement of agricultural production and income and rural development, have made us more qualified, capable and confident to fight the tough battle of agricultural non-point source pollution prevention and control.

  Three, to "one control, two reduction and three basics" as the key task, to fight the battle against agricultural non-point source pollution.

  Since the 18th National Congress of the Communist Party of China, General Secretary of the Supreme Leader and other central leading comrades have repeatedly made important instructions on the protection and governance of agricultural ecological environment. General Secretary of the Supreme Leader pointed out that agricultural development should not only put an end to the new debts owed by the ecological environment, but also gradually pay back the old debts, and fight a tough battle for agricultural non-point source pollution control. Premier Li Keqiang proposed that the deterioration of resources and environment should be resolutely suppressed and the overdrawn resources and environment should be rehabilitated. In order to implement a series of deployment requirements of the CPC Central Committee and the State Council, at the beginning of this year, the Ministry of Agriculture, together with relevant departments, successively issued the National Agricultural Sustainable Development Plan (2015-2030), the Agricultural Prominent Environmental Problems Control Plan (2015-2018) and the Implementation Opinions of the Ministry of Agriculture on Fighting the Fight against Agricultural Non-point Source Pollution. Recently, a national on-the-spot meeting on accelerating the transformation of agricultural development mode and a national conference on the protection and governance of agricultural ecological environment have been held in Sichuan, which is an important meeting with milestone significance in the development process of modern agriculture in China. The promulgation of these documents and the convening of the conference have fully deployed and mobilized the protection and governance of agricultural ecological environment. At present, the most important task is to focus on the goal of "one control, two reductions and three basics" and fight a tough battle against agricultural non-point source pollution.

  First, vigorously develop water-saving agriculture.Facing the severe situation of increasingly scarce water resources, it is necessary to increase efforts to develop water-saving agriculture. By strengthening the demonstration of water-saving agriculture, actively promoting water-saving varieties, integration of water and fertilizer, circulating aquaculture and other technologies, the utilization efficiency of water resources will be improved in an all-round way. Actively promote the comprehensive reform of agricultural water price. Coordinate the promotion of water ecological protection and management in river basins, and actively carry out the construction of demonstration zones for comprehensive prevention and control of agricultural non-point source pollution in key river basins such as Taihu Lake, Erhai Lake, Chaohu Lake and Three Gorges Reservoir Area. By 2020, the national agricultural irrigation water consumption will be controlled within 372 billion cubic meters, and the effective utilization coefficient of farmland irrigation water will reach 0.55.

  The second is to implement the zero growth action of chemical fertilizers.The key to reducing fertilizer application is to establish the concept of green yield increase, vigorously promote scientific fertilization, improve the accuracy and utilization rate of fertilizer use, and encourage farmers to use more green manure and farmyard manure. The key point is to expand the application scope of soil testing and formula fertilization, and promote the formula fertilizer to enter the village and enter the field. At the same time, it is necessary to actively promote the research and development and promotion of new fertilizer products, and integrate and promote high-efficiency fertilization technologies such as simultaneous sowing of seeds and fertilizers and deep application of fertilizers. It is necessary to combine the construction of high-standard farmland, vigorously carry out the action of protecting and improving the quality of cultivated land, study and use subsidies to encourage and guide farmers to promote straw returning, planting green manure, accumulating farmyard manure and increasing the application of organic manure, rationally adjust the fertilization structure, and strive to improve the internal quality of cultivated land. Strive to achieve more than 90% coverage of soil testing and formula fertilization technology, more than 40% utilization rate of chemical fertilizers, and zero growth in the use of chemical fertilizers for major crops in China by 2020.

  The third is to implement the zero growth action of pesticides.Adhere to comprehensive management, treat both the symptoms and the root causes, and realize scientific and accurate drug application. Strengthen the management of pesticide use, strengthen source management, and standardize farmers’ use of pesticides. Fully implement the fixed-point management of highly toxic pesticides and establish a traceability system for highly toxic pesticides. We will implement pilot projects for the use of low-toxic and low-residue pesticides, gradually expand the scope of subsidy projects, and accelerate the popularization and application of biological pesticides and high-efficiency, low-toxic and low-residue pesticides. Encourage agricultural socialized service organizations to provide guidance and services for farmers to use pesticides, and vigorously promote the integration of specialized unified prevention and control and green prevention and control. Ensure that by 2020, the coverage rate of green prevention and control of major crop pests and diseases will reach more than 30%, the utilization rate of pesticides will reach more than 40%, and the use of pesticides for major crops in China will achieve zero growth.

  The fourth is to promote the prevention and control of aquaculture pollution.Overall consideration of environmental carrying capacity and pollution prevention requirements of livestock and poultry breeding, scientific planning and layout of livestock and poultry breeding. Promote standardized scale farming, supporting the construction of treatment and utilization facilities, improve facility farming technology, improve technical and equipment conditions, and encourage and support the implementation of household collection and centralized treatment of livestock and poultry manure in densely populated areas. Strengthen the construction of demonstration farms for healthy aquaculture, and popularize aquaculture technologies such as industrialized circulating aquaculture, pond ecological circulating aquaculture and bottom sewage of large-surface cage aquaculture. By 2020, more than 75% of large-scale livestock and poultry farms (districts) will build supporting facilities for waste storage, treatment and utilization.

  Fifth, efforts should be made to solve the residual film pollution in farmland.Accelerate the revision of mulching film standards, strictly stipulate the thickness and tensile strength of mulching film, prohibit the production and use of substandard mulching film, and ensure that the residual mulching film in farmland can be recycled from the source. Increase financial support for technical subsidies for dry farming. Carry out regional demonstration of farmland residual film recycling, support the construction of plastic film recycling outlets and waste plastic film processing capacity, gradually improve the recycling network, and innovate the plastic film recycling and reuse mechanism. Accelerate the research and development of eco-friendly degradable plastic film and plastic film residue picking and processing machinery, and establish and improve the evaluation system of degradable plastic film. Ensure that by 2020, the recovery rate of agricultural film will reach more than 80% in the current season.

  Sixth, carry out in-depth utilization of straw resources.According to the idea of "policy support, demonstration and guidance, focusing on agriculture, industrial development and market operation", we will promote the full utilization of straw "five materials" according to local conditions. It is necessary to further support the demonstration of new technologies such as straw harvesting machinery returning to the field, green and yellow storage for feed, microbial decay and solidification carbonization gasification, and study and introduce policies and measures such as enjoying the price of agricultural electricity for straw primary processing, incorporating storage and storage land into agricultural land management and credit support. Accelerate the establishment of a market-oriented mechanism for straw storage and transportation, reduce the cost of storage and transportation, and promote the scale and industrialization of comprehensive utilization of straw. In the key areas of air pollution, start the construction of demonstration counties for comprehensive utilization of straw, and fundamentally solve the problem of open burning of straw. Achieve the goal that the comprehensive utilization rate of straw will reach over 85% by 2020.

  Agricultural non-point source pollution control is a tough battle and a protracted war. We need to base ourselves on the present and focus on the long-term. We should focus on five "enhancements" and five "enhancements", strengthen top-level design, increase planning and implementation, strengthen legal promotion, increase supervision and law enforcement, strengthen financial security, increase social participation, strengthen monitoring and early warning, increase scientific and technological support, strengthen policy creation, increase supervision and assessment, and take multiple measures to ensure implementation.

Entrepreneurship on the Road: Winning Brilliant Opportunities for Life

Implementing the innovation-driven development strategy and promoting "mass entrepreneurship and innovation" is a major deployment made by the CPC Central Committee. As for starting a business, we have heard the story that some entrepreneurs often raise millions of dollars and get rich overnight. Is it really that easy to start a business? It is also said that the success rate of starting a business is less than 1%, and a startup enterprise may face death if it is not careful. Is entrepreneurship really that terrible? The series report "Entrepreneurship on the Road" tells the ups and downs of these young people’s entrepreneurial stories.

China CDC: It is recommended to vaccinate against influenza as soon as possible, especially for the elderly and children.

  CCTV News:The National Health and Wellness Commission held a press conference on December 2 to introduce the prevention and treatment of respiratory diseases in winter and answer media questions.

Xinhua News Agency: Vaccine has played a key role in the prevention and control of influenza. At present, influenza has entered the high season. Is it too late to vaccinate now?

Wang Dayan, Director of National Influenza Center, Institute of Virology, China CDC:Among the prevalent respiratory diseases, influenza, COVID-19 and pneumococcal infection all have corresponding types of vaccines. The influenza vaccine has been used in the world and China for decades. Scientific research and vaccination practice have fully proved that the influenza vaccine is safe, effective and a mature vaccine. Influenza vaccination can effectively reduce infection, even if it is infected, it can also reduce the incidence, and even if it is infected, it can also reduce the severity of the disease.

At present, it is the high season of influenza, and it is still effective to vaccinate people who have not been vaccinated with influenza before. It is recommended that you vaccinate with influenza as soon as possible. Here, I especially point out that people over 6 months can be vaccinated with influenza, especially for high-risk people such as children, the elderly and patients with chronic diseases. After being infected with influenza, the risk of severe illness is higher. Vaccination with influenza can effectively reduce the risk of developing into severe illness and death. I hope everyone will actively vaccinate.

Practice at home and abroad has proved that the use of vaccine is one of the most economical and effective preventive measures, and the vaccine is safe. As long as it is vaccinated in professional institutions as required, it can have good results, especially for the elderly and children, and should actively vaccinate against influenza to ensure the normal pace of life and study.

Baoding Xu Shui: Meteorological service escort greenhouse onion planting

On February 18th, the service personnel of Xushui Meteorological Bureau in Baoding City, Hebei Province came to Beiqinggong Village, Zhengcun Town, to investigate the demand for meteorological services for onion planting, and to protect the characteristic industries.

Service personnel walked into the greenhouse, had in-depth communication with growers, understood the demand for meteorological services, and reminded growers to pay close attention to the latest meteorological forecast and early warning information in view of the recent low temperature and windy weather, so as to make greenhouse management more scientific and effective.

On February 18th, the meteorological service personnel of Xushui Meteorological Bureau inspected the growth of shallots. Li Anqi photography

Combined with the meteorological service demand learned this time, Xushui Meteorological Bureau will make special meteorological service materials and send them to growers through SMS, WeChat and other channels in time, so as to contribute meteorological power to increase agricultural production and farmers’ income.

(Author: Li Anqi Editor: Su Jessie)

Aya Sugimoto appeared naked in an advertisement to protect animals and refused fur

Actress Aya Sugimoto was recently invited to shoot a group of public service advertisements for PETA, an animal protection association. On the 17th, she took a formal photo shoot in a studio in Tokyo.



  Although she was used to nudity in filming, Aya Sugimoto felt a different sense of tension that day. Only one piece with the words "Fur? It’s better to be naked. "The advertisement board covers her chest. She said," So far, I feel naked is the feeling of wearing another suit, but this time I have a different sense of tension. I seem to have taken off all my clothes. " Having said that, the actress, who is famous for her sexy and erotic lines, still showed a provocative and dangerous expression when facing the camera. "I stopped wearing fur two years ago, hoping I could face the eyes of those dead animals." It seems that Erotic Queen still has a positive attitude and decisive action in environmental protection. I believe this is also the place that PETA invited her to appear in this group of advertisements.